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Article
Age-related differences in interferon regulatory factor-4 and -5 signaling in ischemic brains of mice
Stroke is a disease that mainly affects the elderly. Since the age-related differences in stroke have not been well studied, modeling stroke in aged animals is clinically more relevant. The inflammatory respon...
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Article
Regulation of microglial activation in stroke
When ischemic stroke occurs, oxygen and energy depletion triggers a cascade of events, including inflammatory responses, glutamate excitotoxicity, oxidative stress, and apoptosis that result in a profound brai...