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    Article

    Vagal-α7nAChR signaling is required for lung anti-inflammatory responses and arginase 1 expression during an influenza infection

    Vagal circuit-α7 nicotinic acetylcholine receptor (α7nAChR, coded by Chrna7) signaling can modulate lung proinflammatory responses. Arginase 1 (ARG1) plays a crucial role in the resolution of lung inflammation. H...

    Zhao-wei Gao, Ling Li, Yuan-yuan Huang, Cai-qi Zhao in Acta Pharmacologica Sinica (2021)

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    Article

    Serum adenosine deaminase activity is increased in systemic lupus erythematosus patients and correlated with disease activity

    Adenosine deaminase (ADA) has been found to be involved in autoimmune disease progression. To assess the potential application of serum ADA activity in diagnosing systemic lupus erythematosus (SLE) and evaluat...

    Zhao-wei Gao, Guan-hua Zhao, Zhe Zhang, **g Huang, Zi-yue Li in Immunologic Research (2018)

  3. Article

    Open Access

    CD73 promotes proliferation and migration of human cervical cancer cells independent of its enzyme activity

    CD73 has both enzymatic and non-enzymatic functions in cells. As a nucleotidase, CD73 plays its enzymatic function by catalyzing the hydrolysis of AMP into adenosine and phosphate. In addition to this, accumul...

    Zhao-wei Gao, Hui-** Wang, Fang Lin, ** Wang, Min Long, Hui-zhong Zhang in BMC Cancer (2017)

  4. Article

    Open Access

    The role of adenosinergic pathway in human autoimmune diseases

    Autoimmune diseases are characterized by the abnormal immune response against self-tissue, which are caused by the failure of nature immune homeostasis. Nature immune homeostasis represents the normal state o...

    Ke Dong, Zhao-wei Gao, Hui-zhong Zhang in Immunologic Research (2016)