5,564 Result(s)
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Zhao-**ong Zhang
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Article
Brain-Targeting Emodin Mitigates Ischemic Stroke via Inhibiting AQP4-Mediated Swelling and Neuroinflammation
Failure to achieve target-specific delivery to ischemic brain sites has hampered the clinical efficacy of newly developed therapies for ischemic stroke. Emodin, an active ingredient isolated from traditional C...
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Article
Aspect category sentiment classification via document-level GAN and POS information
The purpose of aspect-category sentiment classification (ACSC) is to determine the sentiment polarity of the predefined aspect category from the texts. Current methods for ACSC have two main limitations. Since...
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Article
Surface diffraction beamline at the SSRF
BL02U2 of the Shanghai Synchrotron Radiation Facility is a surface diffraction beamline with a photon flux of 5.5 × 1012 photons/s at 10 keV and a beam size of 160 µm × 80 µm at the sample site. It is dedicated t...
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Open AccessGenetic diversity and prevalence of emerging Rickettsiales in Yunnan Province: a large-scale study
Rickettsia and related diseases have been identified as significant global public health threats. This study involved comprehensive field and systematic investigations of various rickettsial organisms in Yunna...
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Isolation and characterization of three DREB-like genes encoding dehydration-responsive element binding proteins in chicory (Cichorium intybus)
Three novel DREB (Dehydration-Responsive Element Binding protein) genes, designated as CiDREB2A, CiDREB5A and CiDREB6A, were individually isolated from chicory (Cichorium intybus L). Based on phylogenetic tree an...
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Article
Mineral transformation and solidification of heavy metals during co-melting of MSWI fly ash with coal fly ash
Melting is an efficient method to turn municipal solid waste incineration (MSWI) fly ash (FA) into non-hazardous material. Coal fly ash (CFA) was selected as the silica-alumina source to carry out co-melting r...
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Open AccessBreaking down barriers: rationalisations and motivation to stop among Chinese male smokers under cigarette dependence
Smoking rationalisation beliefs are a huge barrier to quitting smoking. What types of rationalisations should be emphasised in smoking cessation interventions? Although past literature has confirmed the negati...
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Open AccessATP6V0A1-dependent cholesterol absorption in colorectal cancer cells triggers immunosuppressive signaling to inactivate memory CD8+ T cells
Obesity shapes anti-tumor immunity through lipid metabolism; however, the mechanisms underlying how colorectal cancer (CRC) cells utilize lipids to suppress anti-tumor immunity remain unclear. Here, we show th...
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Correction to: Association Between a Failed Prominence Eruption and the Drainage of Mass from Another Prominence
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Article
Open AccessEstablishment of an ovarian cancer exhausted CD8+T cells-related genes model by integrated analysis of scRNA-seq and bulk RNA-seq
Ovarian cancer (OC) was the fifth leading cause of cancer death and the deadliest gynecological cancer in women. This was largely attributed to its late diagnosis, high therapeutic resistance, and a dearth of ...
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Article
Open AccessWhich one is the best in treating deep venous thrombosis —— percutaneous mechanical thrombectomy, catheter-directed thrombolysis or combination of them?
To compare the treatment outcomes among percutaneous mechanical thrombectomy (PMT) with AngioJet, Catheter-directed thrombolysis (CDT), and a combination of both.
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Article
Open AccessMultiparametric mri-based radiomics nomogram for predicting lymph-vascular space invasion in cervical cancer
To develop and validate a multiparametric magnetic resonance imaging (mpMRI)-based radiomics model for predicting lymph-vascular space invasion (LVSI) of cervical cancer (CC).
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Article
Open AccessPredictors of the prevalence and importance of the observed trinary control system in rural China
Western criminological literature continues to focus on the binary control system (formal vs. informal), while China has long employed the trinary system (formal, semiformal, and informal) in its construction ...
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Article
An efficient preconditioner for linear systems arising from high-order accurate schemes of time fractional diffusion equations
In this paper, we study preconditioners for all-at-once systems arising from the discretization of time-fractional sub-diffusion equations. Due to the use of high-order accurate formulas in time fractional der...
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Dynamic variation of dissolved As, Sb, Fe and S in paddy soil triggered by nitrate loading to overlaying water
Arsenic (As) and antimony (Sb) are toxic elements that usually co-occur in paddy soils due to their chemical similarity. Those elements are redox-sensitive and shift their species across the soil–water interfa...
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Article
Chinese Medicine for Treatment of COVID-19: A Review of Potential Pharmacological Components and Mechanisms
Coronavirus disease 2019 (COVID-19) is an acute infectious respiratory disease that has been prevalent since December 2019. Chinese medicine (CM) has demonstrated its unique advantages in the fight against COV...
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Article
Open AccessTamm-cavity terahertz detector
Efficiently fabricating a cavity that can achieve strong interactions between terahertz waves and matter would allow researchers to exploit the intrinsic properties due to the long wavelength in the terahertz ...
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Article
Open AccessAn optimal combination of four active components in Huangqin decoction for the synergistic sensitization of irinotecan against colorectal cancer
Irinotecan (CPT-11) is a first-line treatment for advanced colorectal cancer (CRC). Four components (baicalin, baicalein, wogonin, and glycyrrhizic acid) derived from Huangqin Decoction (HQD) have been proven ...
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Article
Transformation of A1/A2 Astrocytes Participates in Brain Ischemic Tolerance Induced by Cerebral Ischemic Preconditioning via Inhibiting NDRG2
Cerebral ischemic preconditioning (CIP) has been shown to improve brain ischemic tolerance against subsequent lethal ischemia. Reactive astrocytes play important roles in cerebral ischemia–reperfusion. Recent ...
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Article
Acetylcytidine modification of Amotl1 by N-acetyltransferase 10 contributes to cardiac fibrotic expansion in mice after myocardial infarction
Cardiac fibrosis is a pathological scarring process that impairs cardiac function. N-acetyltransferase 10 (Nat10) is recently identified as the key enzyme for the N4-acetylcytidine (ac4C) modification of mRNAs...
