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  1. No Access

    Article

    Leaf and rhizome transcriptome assembly and expression analysis of genes involved in terpene biosynthesis in Dioscorea opposita

    Dioscorea opposita is a monocotyledonous plant in the Dioscoreaceae family. The rhizome of D. opposita, known as “Dioscoreae rhiaoma” or “Chinese yam”, is not only a well-known traditional Chinese medicine, but a...

    Dianyun Hou, Yaoyao Wang, Ruiying Zhang… in Journal of Plant Biochemistry and Biotechn… (2023)

  2. No Access

    Article

    A New Perspective on Ameliorating Depression-Like Behaviors: Suppressing Neuroinflammation by Upregulating PGC-1α

    Inflammation plays an important role in depression pathology, making it a promising target for ameliorating depression-like behaviors. The peroxisome proliferator-activated receptor gamma coactivator-1 alpha (...

    **nxin Fu, Jie Jiao, Tingting Qin, Jiayu Yu, Qiang Fu… in Neurotoxicity Research (2021)

  3. Article

    Open Access

    Suppressing the Na+/H+ exchanger 1: a new sight to treat depression

    Na+/H+ exchanger 1 (NHE1), an important regulator of intracellular pH (pHi) and extracellular pH (pHe), plays a crucial role in various physiological and pathological processes. However, the role of NHE1 in depre...

    Xueyang Deng, Zhouye Ji, Bingru Xu, Liting Guo, Lixing Xu… in Cell Death & Disease (2019)

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  4. No Access

    Article

    Radix Scutellariae Attenuates CUMS-Induced Depressive-Like Behavior by Promoting Neurogenesis via cAMP/PKA Pathway

    Chronic mild unpredictable stress (CUMS) causes neurogenesis damage in the hippocampus and depressive-like behaviors such as cognitive impairment. Radix Scutellariae from the dry root of Scutellaria baicalensis G...

    Ruyi Zhang, Liting Guo, Zhouye Ji, **aoxi Li, Chenyiyu Zhang… in Neurochemical Research (2018)

  5. No Access

    Article

    Levo-tetrahydropalmatine Attenuates Neuron Apoptosis Induced by Cerebral Ischemia–Reperfusion Injury: Involvement of c-Abl Activation

    Ischemic stroke is one of the most dangerous acute diseases which causes death or deformity. Apoptosis has been shown to play an important role in the development and pathogenesis of cerebral ischemia–reperfus...

    Ruoxi Sun, Yichen Song, Shanshan Li, Zhanqiang Ma… in Journal of Molecular Neuroscience (2018)

  6. No Access

    Article

    Suppressing Receptor-Interacting Protein 140: a New Sight for Salidroside to Treat Cerebral Ischemia

    The purpose of the current study was to detect the effect of salidroside (Sal) on cerebral ischemia and explore its potential mechanism. Middle cerebral artery occlusion (MCAO) was performed to investigate the...

    Tong Chen, Zhanqiang Ma, Lingpeng Zhu, Wenjiao Jiang… in Molecular Neurobiology (2016)