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Article
Risk Factors and Predictive Nomogram for Survival in Elderly Patients with Brain Glioma
To determine the factors that contribute to the survival of elderly individuals diagnosed with brain glioma and develop a prognostic nomogram.
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Article
Open AccessCancer stem cells: advances in knowledge and implications for cancer therapy
Cancer stem cells (CSCs), a small subset of cells in tumors that are characterized by self-renewal and continuous proliferation, lead to tumorigenesis, metastasis, and maintain tumor heterogeneity. Cancer cont...
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Article
Characterization of Gut Microbiota in Rats and Rhesus Monkeys After Methamphetamine Self-administration
Methamphetamine (MA) is one of the most abused drugs globally, but the mechanism of its addiction remains unclear. Several animal studies have shown that the gut microbiota (GM) influences addictive behaviors,...
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Article
Open AccessEpidemiological and genomic characteristics of global blaNDM-carrying Escherichia coli
Escherichia. coli is the most frequent host for New Delhi metallo-β-lactamase (NDM) which hydrolyzes almost all β-lactams except aztreonam. The worldwide spread of blaNDM-carrying E. coli heavily threatens public...
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Article
Phase Equilibria of the CaO-SiO2-CeO2-Al2O3-MgO System at 1300°C and 1400°C
The recovery of rare-earth elements (REEs) from rare-earth blast furnace slag (RE-BFS) is crucial for advancing the circular economy. However, the development of related processes is significantly hindered by ...
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Article
Open AccessREEP3 is a potential diagnostic and prognostic biomarker correlated with immune infiltration in pancreatic cancer
Receptor Expression-Enhancing Protein 3 (REEP3) serves as a pivotal enzyme crucial for endoplasmic reticulum (ER) clearance during mitosis and is implicated in the advancement of diverse malignancies. Nonethel...
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Article
Open AccessHigh-grade metamorphism of banded iron formations: the role of saline fluids in promoting the growth of pyroxene and garnet reaction textures along magnetite-quartz grain boundaries
Metamorphosed banded iron formation (BIF) in granulite-amphibolite facies, tonalitic orthogneisses from a series of locations in the Kolli Massif of southern India are described and analysed with regard to the...
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Article
A retrospective study of ovarian tissue cryopreservation in female patients with hematological diseases for fertility preservation
To investigate the effect and safety of ovarian tissue cryopreservation (OTC) for fertility preservation in female patients with hematological diseases.
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Article
Brain Transcriptome Analysis Reveals Metabolic Changes Adapting to Hyperhaline or Hypohaline Environments in Spotted Scat (Scatophagus argus)
The fish brain is crucial for adjusting to environmental changes. Metabolic changes play a vital role in the adaptation to salinity change in aquatic animals. However, few studies have evaluated the responses ...
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Article
Open AccessSynergistic effects of Smac mimetic APG-1387 with anti-PD-1 antibody are attributed to increased CD3 + NK1.1 + cell recruitment secondary to induction of cytokines from tumor cells
Immune checkpoint inhibitors are approved for the treatment of various tumors, but the response rate is not satisfactory in certain malignancies. Inhibitor of apoptosis proteins (IAP) ubiquitin-E3 ligase activ...
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Article
Two New Aromatic Sesquiterpenes from the Leaves of Nicotiana tabacum and Their Aroma Character
Two new aromatic sesquiterpenes, 7-isopropyl-2,2,5-trimethyl-2H-chromene (1) and 7-isopropyl-5- (methoxymethyl)-2,2-dimethyl-2H-chromene (2), were isolated from the leaves of Nicotiana tabacum (a mutant tobacco f...
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Article
Effect of Electric Field on the Microstructure and Properties of NiAl Alloy Sheet Prepared by Foil Reaction Synthesis
NiAl alloy sheet was successfully prepared using current-assisted sintering, thus verifying the possibility of preparing a NiAl thin-wall component by current-assisted sintering and foil/foil reaction synthesi...
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Article
Open AccessImmunophenotype of lymphocytes and real-world outcome of COVID-19 infection in children with hematology and oncology
Patients with immunocompromise were suspected to encounter a high risk for severe coronavirus disease 2019 (COVID-19) infection on early period; however, data is lacking nowadays and immune response remain unc...
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Article
Open AccessGEN1 as a risk factor for human congenital anomalies of the kidney and urinary tract
Congenital anomalies of the kidney and urinary tract (CAKUT) are prevalent birth defects. Although pathogenic CAKUT genes are known, they are insufficient to reveal the causes for all patients. Our previous st...
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Article
Open AccessA new TROP2-targeting antibody-drug conjugate shows potent antitumor efficacy in breast and lung cancers
Trophoblast cell surface antigen 2 (Trop2) is considered to be an attractive therapeutic target in cancer treatments. We previously generated a new humanized anti-Trop2 antibody named hIMB1636, and designated ...
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Article
Open AccessThe value of machine learning based on CT radiomics in the preoperative identification of peripheral nerve invasion in colorectal cancer: a two-center study
We aimed to explore the application value of various machine learning (ML) algorithms based on multicenter CT radiomics in identifying peripheral nerve invasion (PNI) of colorectal cancer (CRC).
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Article
Pre-Cryogenian integrative stratigraphy, biotas, and paleogeographical evolution of the Qinghai-Tibetan Plateau and its surrounding areas
The composition and geological evolution of pre-Cryogenian material in the Tibetan Plateau and its surrounding areas have played an important role in studying the formation and evolution of early supercontinen...
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Article
Open AccessLncRNA SNHG26 promotes gastric cancer progression and metastasis by inducing c-Myc protein translation and an energy metabolism positive feedback loop
Metastasis is a bottleneck in cancer treatment. Studies have shown the pivotal roles of long noncoding RNAs (lncRNAs) in regulating cancer metastasis; however, our understanding of lncRNAs in gastric cancer (G...
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Article
Influence of Co-do** on Soft Spark Micro-arc Oxidation on ZrO2–AZ91D Magnesium Alloy
Magnesium (Mg) and its alloys face challenges in clinical applications due to their high degradation rates and low antibacterial properties. To overcome these challenges, this study employed an electrolyte con...
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Article
Multifunctional cellulose composite films with dual-continuous CNT/BN networks for synchronously enhanced electromagnetic interference shielding ability and thermal conductivity
Multifunctional materials with high electromagnetic interference (EMI) shielding effectiveness and thermal conductivity (TC) are an essential guarantee for the rapid advancement of next-generation electronic p...
