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    Open Access

    CKM and TERT dual promoters drive CRISPR–dCas9 to specifically inhibit the malignant behavior of osteosarcoma cells

    Improvements in treatment and chemotherapy have increased the survival rate of osteosarcoma, but overall efficacy remains low, highlighting the need for new gene therapy methods. Clustered regularly interspace...

    Yawei Hu, Hao Zhang, Zengfeng Guo, Jianhua Zhou in Cellular & Molecular Biology Letters (2023)