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Article
Open AccessPhenotypic and genetic characterization of hypervirulent Klebsiella pneumoniae in patients with liver abscess and ventilator-associated pneumonia
Ventilator-associated pneumonia (VAP) and pyogenic liver abscess (PLA) due to Klebsiella pneumoniae infection can trigger life-threatening malignant consequences, however, there are few studies on the strain-asso...
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Article
Open AccessLactylation of METTL16 promotes cuproptosis via m6A-modification on FDX1 mRNA in gastric cancer
Cuproptosis, caused by excessively high copper concentrations, is urgently exploited as a potential cancer therapeutic. However, the mechanisms underlying the initiation, propagation, and ultimate execution of...
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Article
Open AccessPUMD: a PU learning-based malicious domain detection framework
Domain name system (DNS), as one of the most critical internet infrastructure, has been abused by various cyber attacks. Current malicious domain detection capabilities are limited by insufficient credible lab...
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Article
Open AccessPrevalence and molecular characterization of methicillin-resistant Staphylococcus aureus with mupirocin, fusidic acid and/or retapamulin resistance
The data on the prevalence of resistance to mupirocin (MUP), fusidic acid (FA) and retapamulin (RET) in methicillin-resistant Staphylococcus aureus (MRSA) from China are still limited. This study aimed to examine...
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Chapter and Conference Paper
Social Recommendation in Heterogeneous Evolving Relation Network
The appearance and growth of social networking brings an exponential growth of information. One of the main solutions proposed for this information overload problem are recommender systems, which provide perso...
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Article
Open AccessExploring the whole standard operating procedure for phage therapy in clinical practice
We have entered the post-antibiotic era. Phage therapy has recently been given renewed attention because bacteriophages are easily available and can kill bacteria. Many reports have demonstrated successful pha...
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Chapter and Conference Paper
Mention Recommendation with Context-Aware Probabilistic Matrix Factorization
Mention as a key feature on social networks can break through the effect of structural trap** and expand the visibility of a message. Although existing works usually use rank learning as implementation strat...
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Article
Open AccessCharacterization and complete genome of the virulent Myoviridae phage JD007 active against a variety of Staphylococcus aureus isolates from different hospitals in Shanghai, China
The implementation of phage therapy is re-emerging with the increase in widespread antibiotic-resistant bacteria.
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Article
Open AccessSafety assessment of Staphylococcus phages of the family Myoviridae based on complete genome sequences
Staphylococcus phages of the Myoviridae family have a wide host range and potential applications in phage therapy. In this report, safety assessments of these phages were conducted based on their complete genome ...
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Article
Drug resistance and virulence of uropathogenic Escherichia coli from Shanghai, China
Uropathogenic Escherichia coli (UPEC) is the major cause of urinary tract infections (UTIs). In the present study, 198 E. coli isolates from patients with UTIs in Shanghai in 2008 were examined by susceptibility ...
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Article
Open AccessComplex sputum microbial composition in patients with pulmonary tuberculosis
An increasing number of studies have implicated the microbiome in certain diseases, especially chronic diseases. In this study, the bacterial communities in the sputum of pulmonary tuberculosis patients were e...
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Article
Comparative proteogenomic analysis of the Leptospira interrogans virulence-attenuated strain IPAV against the pathogenic strain 56601
The virulence-attenuated Leptospira interrogans serovar Lai strain IPAV was derived by prolonged laboratory passage from a highly virulent ancestral strain isolated in China. We studied the genetic variations of ...
