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Article
Open AccessHippo kinases Mst1 and Mst2 maintain NK cell homeostasis by orchestrating metabolic state and transcriptional activity
Natural killer (NK) cells play a crucial role in immune response against viral infections and tumors. However, further investigation is needed to better understand the key molecules responsible for determining...
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Article
Colorimetric Detection of Acid Phosphatase and Malathion Using NiCo2O4 Nanosheets as Peroxidase-Mimicking Activity
The establishment of a low-cost and facile approach for the assay of acid phosphatase (ACP) and its inhibitor is a research focus. In this paper, we successfully synthesized NiCo2O4 nanosheets with peroxidase-mim...
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Article
Open AccessAnalytics of motivational factors of educational video games: LDA topic modeling and the 6 C’s learning motivation model
This research studies the motivational factors used in educational video games through the lens of 6 C’s learning motivation model with text mining of the players’ reviews and comments. This research seeks to ...
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Article
Open AccessExploring the preparation of YbBa2Cu3O7−y superconductor in flowing oxygen atmosphere
REBCO has been used extensively as coated conductors applied to superconducting magnets due to its exceptional superconducting properties. As a REBCO superconductor, YbBa2Cu3O7−y (Yb123) has a low melting tempera...
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Article
Open AccessThe application of JAK inhibitors in the peri-transplantation period of hematopoietic stem cell transplantation for myelofibrosis
Myelofibrosis (MF) is a myeloproliferative neoplasm (MPN) with a poor prognosis, and allogeneic hematopoietic stem cell transplantation (allo-HSCT) is the only treatment with curative potential. Ruxolitinib, a...
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Article
MOF@lignocellulosic nanofibril aerogel designed by carboxymethylated nanocellulose bridging for thermal insulation and fire retardancy
Under the global issues of environmental pollution and energy crisis, cellulose nanofiber (CNF)–based aerogels have attracted great attention for energy-efficient building application. For safety concern, meta...
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Development and initial validation of the Psoriatic Arthritis Screening Questionnaire: a cross-sectional study in Chinese population
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Article
Hesperetin attenuates cognitive dysfunction via SIRT6/NLRP3 pathway in scopolamine-induced mice
Neuroinflammation is a critical feature in the pathogenesis of neurodegenerative disorders such as Alzheimer’s disease (AD). Hesperetin can exert anti-inflammatory, antioxidant and other neuroprotective effect...
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Article
Towards effective communication with users in the design process: an experimental study on the validity differences of different representation forms in delivering conceptual design information
Users’ participation in early stages of the product innovation process is conducive to accelerating the convergence of the design process. To provide insights into the design or selection of a design represent...
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Improved V-Net lung nodule segmentation method based on selective kernel
Segmentation algorithm based on deep learning has become the main method of pulmonary nodules segmentation; nevertheless, the accuracy and lightweight of most such models are difficult to coexist. In order to ...
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Article
Oxidating liquid metal interface integrated capacitive pressure detection
The characteristics of real-time monitoring and flexible integration based on passive capacitive detection are becoming the preferred sensing strategy for wearable devices. However, the currently designed capa...
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Article
Multiphase flow physics of room temperature liquid metals and its applications
Multiphase flow existing everywhere in the motion evolution of nature, industrial processes, and daily life, has been an interdisciplinary cutting-edge frontier covering rather diverse disciplines. Traditional...
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Article
Open AccessEvaluation of the biocontrol potential of the fungus Botrytis euroamericana strain HZ-011 for herbicidal activity
Weeds in farmland seriously threaten crop yield and cause huge economic losses. Due to the extensive use of chemical herbicides, a series of problems have been arisen, such as environmental pollution, soil deg...
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Risk Factors and Quality of Life in Patients with Diffuse Pouchitis After Ileal Pouch Anal Anastomosis According to the Chicago Classification for J Pouch: a Retrospective Multicenter Cohort Study in China
Pouchitis is a common late complication in patients with ulcerative colitis (UC) who undergo ileal pouch–anal anastomosis (IPAA). The heterogeneous nature of the clinical and endoscopic presentations could aff...
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Article
Open Accessα7 Nicotinic acetylcholine receptor: a key receptor in the cholinergic anti-inflammatory pathway exerting an antidepressant effect
Depression is a common mental illness, which is related to monoamine neurotransmitters and the dysfunction of the cholinergic, immune, glutamatergic, and neuroendocrine systems. The hypothesis of monoamine neu...
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Article
Open AccessSynthesis and biological evaluation of substituted acetamide derivatives as potential butyrylcholinestrase inhibitors
Alzheimer’s disease (AD) is the most common type of age-related dementia. Inhibition of butyrylcholinesterase (BChE) emerge as an effective therapeutic target for AD. A series of new substituted acetamide deri...
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Article
Open AccessKai-**n-San protects against mitochondrial dysfunction in Alzheimer’s disease through SIRT3/NLRP3 pathway
Kai-**n-San (KXS) has been reported to have a good curative impact on dementia. The purpose of the study was to determine whether KXS might ameliorate cognitive deficits in APP/PS1 mice and to evaluate its neu...
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Article
Image inpainting algorithm based on tensor decomposition and weighted nuclear norm
For a damaged image, recovering an image with missing entire rows or columns is a challenging problem arising in many real applications, such as digital image inpainting. For this kind of information missing s...
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Chapter
Moscow
Chapter 2 consists of Liu’s diaries from his departure for China’s Moscow embassy in June 1940 to his recall to China in December 1944. Here he records his work as embassy counsellor both in Moscow and in the ...
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Chapter
Ürümchi
Chapter 3 spans Liu’s service as Special Commissioner of China’s Foreign Ministry in **njiang from late 1944 until the province was seized by the Chinese Communist Party in late 1949. During this time Liu also...