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Open AccessExploring Aeromonas dhakensis in Aldabra giant tortoises: a debut report and genetic characterization
Aeromonas dhakensis (A. dhakensis) is becoming an emerging pathogen worldwide, with an increasingly significant role in animals and human health. It is a ubiquitous bacteria found in terrestrial and aquatic milie...
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Open AccessNomogram incorporating Epstein-Barr virus DNA and a novel immune-nutritional marker for survival prediction in nasopharyngeal carcinoma
Since Immune response, nutritional status and Epstein–Barr Virus (EBV) DNA status have been confirmed to be relevant to the prognosis of patients with nasopharyngeal carcinoma (NPC), we believe that the combin...
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Routing Strategy for Distributed Quantum Circuit based on Optimized Gate Transmission Direction
Due to the limitations of quantum device manufacturing technology, the number of qubits in current quantum computing devices is still relatively limited. Distributed quantum computing, as an emerging quantum c...
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Open AccessImpact of sex on treatment-related adverse effects and prognosis in nasopharyngeal carcinoma
In nasopharyngeal cancer (NPC), women have a lower incidence and mortality rate than men. Whether sex influences the prognosis of NPC patients remains debatable. We retrospectively examined the influence of se...
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USP51 facilitates colorectal cancer stemness and chemoresistance by forming a positive feed-forward loop with HIF1A
In the current study, we have shown that USP51 promotes colorectal cancer stemness and chemoresistance, and high expression of USP51 predicts survival disadvantage in colorectal cancer patients. Mechanically, ...
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DC vaccine enhances CAR-T cell antitumor activity by overcoming T cell exhaustion and promoting T cell infiltration in solid tumors
Great success has been achieved in CAR-T cell immunotherapy in the treatment of hematological tumors. However, it is particularly difficult in solid tumors, because CAR-T is difficult to enter interior and exe...
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Open Access3-Bromopyruvate overcomes cetuximab resistance in human colorectal cancer cells by inducing autophagy-dependent ferroptosis
Colorectal cancer (CRC) remains a leading cause of cancer-related death worldwide. Cetuximab, in combination with chemotherapy, is effective for treating patients with wild-type KRAS/BRAF metastatic CRC (mCRC)...
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Open AccessSystemic immune-inflammation index during treatment predicts prognosis and guides clinical treatment in patients with nasopharyngeal carcinoma
Systemic immune-inflammation index (SII) has been demonstrated to be closely associated with the poor prognosis of nasopharyngeal carcinoma (NPC). However, the role of SII during treatment of NPC has not been ...
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Article
Open AccessCombination of smoking and Epstein-Barr virus DNA is a predictor of poor prognosis for nasopharyngeal carcinoma: a long-term follow-up retrospective study
This retrospective study was performed to determine the prognostic potential of smoking and its combination with pre-treatment plasma Epstein-Barr virus (EBV) DNA levels in patients with nasopharyngeal carcino...
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Article
Open AccessPrognostic value of systemic inflammation response index in nasopharyngeal carcinoma with negative Epstein-Barr virus DNA
Inflammatory parameters and Epstein–Barr virus (EBV) DNA status have been confirmed to be associated with prognosis in nasopharyngeal carcinoma (NPC) patients. However, there are few in-depth studies on the pr...
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Chapter
Concept Mathematics
Part III deals with the very definition of conceptual mathematics and then a discussion of first attempts to generate a systematic approach to conceptual mathematics.
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Chapter
Semiotics
This chapter gives an overview of semiotics as developed by Charles Sanders Peirce, Ferdinand de Saussure, Louis Hjelmslev, and Roland Barthes.
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Chapter
Semantic Representations
This chapter opens the question about the semantic “loading” of a mathematical concept. This representation relates to the categories of H-jets, where concept are conceived as “sources” of a semantic extension...
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Chapter
Applications and Consequences
Music (and more generally the arts) creates semiotic structures independently of ‘external’ reference contents. We discuss this qualification as a conceptual challenge.
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Chapter
Motivation and Background
We present the motivation for the development of this functorial semiotics as a bridge between Human Intelligence and Artificial Intelligence.
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Chapter
Functorial Semantics Category
This chapter presents the category of functorial semantics, which formalizes the semiotic objects together with the connecting morphisms. These objects are called H-jets, “H” standing for Hjelmslev, who introd...
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Chapter
Semantic and Expressive Topology
This chapter presents a (classical) topology on H-jet collections that relates to semantic aspects. Dually, we shall introduce an expressive topology.
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Chapter
Yoneda
We discuss some global consequences of Yoneda’s Lemma and its philosophy.
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Chapter
Cech Cohomology
We discuss two approaches to Cech cohomology: function spaces for global filters, and functorial cohomology associated with the semantic topology.
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Chapter
Conclusions and Perspectives
This chapter reviews how the mathematics of new concepts of music that we discuss in the book can be used to better understand creativity and its logic. The reading of this book will support your ability to be...
