4 Result(s)

Article

VISTA drives macrophages towards a pro-tumoral phenotype that promotes cancer cell phagocytosis yet down-regulates T cell responses

VISTA is a well-known immune checkpoint in T cell biology, but its role in innate immunity is less established. Here, we investigated the role of VISTA on anticancer macrophage immunity, with a focus on phagoc...

Yusheng Lin, Ghizlane Choukrani, Lena Dubbel… in Experimental Hematology & Oncology (2024)

Article

Increased circulating FGF21 level predicts the burden of metabolic demands and risk of vascular diseases in adults with type 2 diabetes

Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder characterized by chronic hyperglycemia and metabolic stress, involved in the stepwise development of cardiovascular complications. Fibroblast gro...

Zhen Liu, Yue Peng, Supeng Li, Yusheng Lin, Yunfeng Huang… in BMC Endocrine Disorders (2023)

Article

Correction: Repurposing dextromethorphan and metformin for treating nicotine-induced cancer by directly targeting CHRNA7 to inhibit JAK2/STAT3/SOX2 signaling

Lu Wang, Liang Du, **ao **ong, Yusheng Lin, Jianlin Zhu, Zhimeng Yao… in Oncogene (2021)

Article

Repurposing dextromethorphan and metformin for treating nicotine-induced cancer by directly targeting CHRNA7 to inhibit JAK2/STAT3/SOX2 signaling

Smoking is one of the most impactful lifestyle-related risk factors in many cancer types including esophageal squamous cell carcinoma (ESCC). As the major component of tobacco and e-cigarettes, nicotine is not...

Lu Wang, Liang Du, **ao **ong, Yusheng Lin, Jianlin Zhu, Zhimeng Yao… in Oncogene (2021)