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Metformin protects human lens epithelial cells from high glucose-induced senescence and autophagy inhibition by upregulating SIRT1

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  1. Article

    Open Access

    Goldenhar syndrome with limbal neoformation, microtia and skeletal deformities: a case report and literature review

    To report a case of a 4-year-old patient with Goldenhar syndrome.

    Yushan Fu, Haotian Yu, Jiajia Zhang, Nan Zhou in BMC Ophthalmology (2024)

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  2. Article

    Open Access

    Metformin protects lens epithelial cells against senescence in a naturally aged mouse model

    The senescence of lens epithelial cells (LECs) is a major factor leading to age-related cataract (ARC). ARC results in visual impairment and severe vision loss in elderly patients. However, the specific mechan...

    Mengmeng Chen, Yushan Fu, Xu Wang, Ruitong Wu, Dongmei Su, Nan Zhou… in Cell Death Discovery (2022)

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