-
Article
Open AccessSystemic immune-inflammation index and in-stent restenosis in patients with acute coronary syndrome: a single-center retrospective study
In-stent restenosis (ISR) has been shown to be correlated with inflammation. This study aimed to examine the relationship between systemic immune-inflammation index (SII, an innovative inflammatory biomarker) ...
-
Chapter and Conference Paper
A Dynamic Linear Bias Incorporation Scheme for Nonnegative Latent Factor Analysis
High-Dimensional and Incomplete (HDI) data is commonly encountered in big data-related applications like social network services systems, which are concerning limited interactions among numerous nodes. Knowledge ...
-
Article
Open AccessImportant parameters should be paid attention in PTMC radiofrequency ablation
In order to provide clinical references for the RFA procedure and to study the pivotal factors affecting the recovery time of radiofrequency ablation (RFA) in patients with papillary thyroid microcarcinoma (PT...
-
Article
RNA sequencing-based optimization of biological lipid droplets for sonodynamic therapy to reverse tumor hypoxia and elicit robust immune response
Mitochondria-targeted sonodynamic therapy (SDT) is a promising strategy to inhibit tumor growth and activate the anti-tumor immune responses. Identifying the mechanisms underlying mitochondria-targeted SDT, fu...
-
Chapter and Conference Paper
Proximal Symmetric Non-negative Latent Factor Analysis: A Novel Approach to Highly-Accurate Representation of Undirected Weighted Networks
An undirected weighted network (UWN) is constantly encountered in various big data-related applications. A UWN’s topological information can be expressed by a Symmetric, High-dimensional and Incomplete (SHDI) mat...
-
Article
Open AccessTiSe2-mediated sonodynamic and checkpoint blockade combined immunotherapy in hypoxic pancreatic cancer
Pancreatic cancer remains among the most prevalent and aggressive forms of cancer. While immunotherapeutic treatment strategies have shown some promise in affected patients, the benefits of these interventions...
-
Article
NOD2 is involved in regulating odontogenic differentiation of DPSCs suppressed by MDP through NF-κB/p65 signaling
Dental pulp stem cells (DPSCs) are well known for their capable of both self-renewal and multilineage differentiation. Dental tissue diseases, include caries, are often accompanied by inflammatory microenviron...
-
Article
Association between serum folate levels and blood concentrations of cadmium and lead in US adults
Folate may be involved in the detoxification of heavy metals. This has been demonstrated in animal studies, in in vivo and in vitro studies, and clinical evaluations. However, knowledge regarding the associations...
-
Article
Immobilization of Thermostable β-Glucosidase and α-l-Rhamnosidase from Dictyoglomus thermophilum DSM3960 and Their Cooperated Biotransformation of Total Flavonoids Extract from Epimedium into Icaritin
The thermostable GH3 family β-glucosidase DthBgl3 and thermostable GH78 family α-l-rhamnosidase DthRha from Dictyoglomus thermophilum DSM3960 were successfully immobilized by industrial amino resin 1000NH. The op...
-
Article
Drug-Metabolizing Cytochrome P450 Enzymes Have Multifarious Influences on Treatment Outcomes
Drug metabolism is a critical process for the removal of unwanted substances from the body. In humans, approximately 80% of oxidative metabolism and almost 50% of the overall elimination of commonly used drugs...
-
Article
Open AccessPI3K/AKT pathway as a key link modulates the multidrug resistance of cancers
Multidrug resistance (MDR) is the dominant challenge in the failure of chemotherapy in cancers. Phosphatidylinositol 3-kinase (PI3K) is a lipid kinase that spreads intracellular signal cascades and regulates a...
-
Chapter and Conference Paper
A Soft Robotic Glove for Hand Rehabilitation Using Pneumatic Actuators with Variable Stiffness
Traditional rigid robots exist many problems in rehabilitation training. Soft robotics is conducive to breaking the limitations of rigid robots. This paper presents a soft wearable device for the rehabilitatio...
-
Chapter and Conference Paper
New Robustness Measures of Communication Networks Against Virus Attacks
The robustness of the communication network is an important measurement of network connectivity after some attacks, such as virus and failure. To evaluate the network robustness, many robustness measures have...
-
Chapter and Conference Paper
Application of DeepWalk Based on Hyperbolic Coordinates on Unsupervised Clustering
In the real world, various information can be represented by graph structure data. For example, interpersonal relationships and protein structure. In recent years, with the development of artificial intellige...
-
Chapter and Conference Paper
High-Efficiency Triangle Counting on the GPU
Triangle counting is an important step in calculating the network clustering confficient and transitivity, and is widely used in important role recognition, spam detection, community discovery, and biological ...
-
Chapter and Conference Paper
Force Analysis and Experiment of Variable Stiffness Soft Actuator Based on Particle Jamming
At present, the jamming mechanism has some problems such as particles rearrangement and elastoplastic deformation. Therefore, this paper proposes a variable stiffness soft actuator based on the combination of ...
-
Chapter and Conference Paper
Multiplex PageRank in Multilayer Networks Considering Shunt
Recently it has been recognized that many complex biological, technological and social networks have a multilayer nature and can be described by multilayer networks. Multilayer networks are formed by a set of ...
-
Article
Open AccessThe Transmission and Evolution of HIV-1 Quasispecies within One Couple: a Follow-up Study based on Next-Generation Sequencing
Next-generation sequencing (NGS) has been successfully used to trace HIV-1 infection. In this study, we investigated the transmission and evolution of HIV-1 quasispecies in a couple infected through heterosexu...
-
Article
An improved local immunization strategy for scale-free networks with a high degree of clustering
The design of immunization strategies is an extremely important issue for disease or computer virus control and prevention. In this paper, we propose an improved local immunization strategy based on node’s cl...
-
Article
Comparative effects of avoidance and immunization on epidemic spreading in a dynamic small-world network with community structure
Considering the actual behavior of people’s short-term travel, we propose a dynamic small-world community network model with tunable community strength which has constant local links and time varying long-rang...
