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Chapter and Conference Paper
Organization and Function of Pathogenicity Genes of Pseudomonas syringae Pathovars phaseolicola and syringae
The ability of a pathogen to multiply and incite disease in its host plant is determined by genes present both in the pathogen and the host. In recent years, the application of molecular genetic tools has resu...
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Article
Inhibition of cytokinesis by overexpression of NudCL that is localized to the centrosome and midbody
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Article
Expression of Matrix Metalloproteinase-9, Type IV Collagen and Vascular Endothelial Growth Factor in Adamantinous Craniopharyngioma
To explore the expression of matrix metalloproteinase 9 (MMP-9), type IV collagen (Col IV) and vascular endothelial growth factor (VEGF) in adamantinomatous craniopharyngioma (ACP) and analyze the correlation ...
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Article
Pterostilbene protects vascular endothelial cells against oxidized low-density lipoprotein-induced apoptosis in vitro and in vivo
Vascular endothelial cell (VEC) apoptosis is the main event occurring during the development of atherosclerosis. Pterostilbene (PT), a natural dimethylated analog of resveratrol, has been the subject of intens...
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Article
Resuscitative Effect of Hyperoxia Fluid on High-Altitude Hemorrhagic Shock in Rats and Antishock Mechanisms
Pathophysiological characteristics of hemorrhagic shock at high altitude are different from that at plain which involve severe injury, high mortality, difficult treatment and compromised liquid tolerance. High...
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Article
Isolation and characterization of acyl homoserine lactone–producing bacteria during an urban river biofilm formation
The presence and diversity of acyl homoserine lactone (AHL)-producers in an urban river biofilm were investigated during 60-day biofilm formation. AHL biosensors detected the presence of AHL-producers in 1–60-...
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Chapter
Secretome of Mesenchymal Stem Cells
Mesenchymal stem cells (MSCs) are a group of heterogeneous non-hematopoietic cells with self-renewal and multi-lineage differentiation potential, and have been widely used for cell-based therapies. While the m...
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Article
Centrosomal protein FOR20 is essential for S-phase progression by recruiting Plk1 to centrosomes
Centrosomes are required for efficient cell cycle progression mainly by orchestrating microtubule dynamics and facilitating G1/S and G2/M transitions. However, the role of centrosomes in S-phase progression is...
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Article
The ITIM-containing receptor LAIR1 is essential for acute myeloid leukaemia development
Conventional strategies are not particularly successful in the treatment of leukaemia, and identification of signalling pathways crucial to the activity of leukaemia stem cells will provide targets for the dev...
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Article
Responses of rose RhACS1 and RhACS2 promoters to abiotic stresses in transgenic Arabidopsis thaliana
Promoter activities of RhACS1 and RhACS2 , two rose genes involved in ethylene biosynthesis, are highly sensitive to vari...
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Article
Open AccessNSC-640358 acts as RXRα ligand to promote TNFα-mediated apoptosis of cancer cell
Retinoid X receptor α (RXRα) and its N-terminally truncated version tRXRα play important roles in tumorigenesis, while some RXRα ligands possess potent anti-cancer activities by targeting and modulating the tu...
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Article
Open AccessAgonist-induced activation of human FFA1 receptor signals to extracellular signal-regulated kinase 1 and 2 through Gq- and Gi-coupled signaling cascades
FFA1 is abundantly expressed in the liver, skeletal muscle, monocytes and nervous system, but is particularly abundant in pancreatic β cells. It is widely believed that FFA1 exerts its regulatory roles in a va...
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Article
Critical effects of epigenetic regulation in pulmonary arterial hypertension
Pulmonary arterial hypertension (PAH) is characterized by persistent pulmonary vasoconstriction and pulmonary vascular remodeling. The pathogenic mechanisms of PAH remain to be fully clarified and measures of ...
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Article
Open AccessTwa1/Gid8 is a β-catenin nuclear retention factor in Wnt signaling and colorectal tumorigenesis
Hyperactivation of Wnt/β-catenin signaling is one of the major causes of human colorectal cancer (CRC). A hallmark of Wnt signaling is the nuclear accumulation of β-catenin. Although β-catenin nuclear import a...
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Article
Open AccessiASPP–PP1 complex is required for cytokinetic abscission by controlling CEP55 dephosphorylation
Cytokinesis is the last step of cell division and is concluded by the abscission of the intercellular bridge that connects two daughter cells. The tight regulation of cytokinesis completion is essential becaus...
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Article
Open AccessLong noncoding RNA gastric cancer-related lncRNA1 mediates gastric malignancy through miRNA-885-3p and cyclin-dependent kinase 4
Gastric cancer (GC) is one of the most common malignancy and the third leading cancer-related death in China. Long noncoding RNAs (lncRNAs) have been implicated in numerous tumors, including GC, however, the m...
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Article
Open AccessWilms’ tumor 1-associating protein plays an aggressive role in diffuse large B-cell lymphoma and forms a complex with BCL6 via Hsp90
Wilms’ tumor 1-associating protein (WTAP) is a nuclear protein, which is ubiquitously expressed in many tissues. Furthermore, in various types of malignancies WTAP is overexpressed and plays a role as an oncog...
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Article
Open AccessRecQL4-Aurora B kinase axis is essential for cellular proliferation, cell cycle progression, and mitotic integrity
Human RecQL4 helicase plays critical roles in the maintenance of genomic stability. Mutations in RecQL4 helicase results in three clinically related autosomal recessive disorders: Rothmund–Thomson syndrome (RT...
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Article
Open AccessA xenograft model for venous malformation
Vascular malformations are defects caused by the abnormal growth of the vasculature. Among them, venous malformation (VM) is an anomaly characterized by slow-flow vascular lesions with abnormally shaped veins,...
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Article
Open AccessCREPT/RPRD1B associates with Aurora B to regulate Cyclin B1 expression for accelerating the G2/M transition in gastric cancer
Gastric cancer, like most of other cancers, has an uncontrolled cell cycle regulated by cyclins and cyclin-dependent kinases (CDKs). In this study, we reported that gastric cancer cells showed an accelerated G...