Skip to main content

and
  1. Article

    Open Access

    Cisplatin resistance-related multi-omics differences and the establishment of machine learning models

    Platinum-based chemotherapies are currently the first-line treatment of non-small cell lung cancer. This study will improve our understanding of the causes of resistance to cisplatin, especially in lung adeno...

    Qihai Sui, Zhencong Chen, Zhengyang Hu, Yiwei Huang in Journal of Translational Medicine (2022)

  2. Article

    Open Access

    Pan-cancer characterization of metabolism-related biomarkers identifies potential therapeutic targets

    Generally, cancer cells undergo metabolic reprogramming to adapt to energetic and biosynthetic requirements that support their uncontrolled proliferation. However, the mutual relationship between two critical ...

    Guoshu Bi, Yunyi Bian, Jiaqi Liang, Jiacheng Yin in Journal of Translational Medicine (2021)

  3. Article

    Open Access

    Knockdown of GTF2E2 inhibits the growth and progression of lung adenocarcinoma via RPS4X in vitro and in vivo

    Lung adenocarcinoma (LUAD) is one of the most common malignancies worldwide. However, the molecular mechanism of LUAD tumorigenesis and development remains unclear. The purpose of this study was to comprehensi...

    Guoshu Bi, Donglin Zhu, Yunyi Bian, Yiwei Huang, Cheng Zhan in Cancer Cell International (2021)

  4. No Access

    Article

    Identification of immune-related gene signature predicting survival in the tumor microenvironment of lung adenocarcinoma

    The tumor microenvironment (TME) plays an essential role in the occurrence and progression of malignancy. The potential prognostic TME-related biomarkers of lung adenocarcinoma (LUAD) remained unclear, which w...

    Mengnan Zhao, Ming Li, Zhencong Chen, Yunyi Bian, Yuansheng Zheng in Immunogenetics (2020)