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Article
Open AccessThe association between heparin sensitivity index and postoperative blood loss in Chinese patients undergoing elective off-pump coronary artery bypass grafting: a single center retrospective study
The heparin sensitivity index (HSI) is closely associated with perioperative ischemic events and increased blood loss in cardiac surgery. Previous studies have produced conflicting results. Therefore, this stu...
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Article
Open AccessHemostatic effects of tranexamic acid in cardiac surgical patients with antiplatelet therapy: a systematic review and meta-analysis
The purpose of the current study was to assess the efficacy of tranexamic acid (TXA) on reducing bleeding in cardiac surgical patients with preoperative antiplatelet therapy (APT).
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Article
Construction of a dual-signal readout platform for effective glutathione S-transferase sensing based on polyethyleneimine-capped silver nanoclusters and cobalt-manganese oxide nanosheets with oxidase-mimicking activity
A novel dual-mode fluorometric and colorimetric sensing platform is reported for determining glutathione S-transferase (GST) by utilizing polyethyleneimine-capped silver nanoclusters (PEI-AgNCs) and cobalt-man...
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Article
Simplified linear analysis model of longitudinal constraint effect of high-speed railway simply-supported bridge under frequent earthquake
The structure of a high-speed railway (HSR) bridge with a track system is complex, and the computational efficiency of seismic analysis for a refine HSR bridge with a track system model (BM) is low. This study...
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Article
Study of the track constraint effect on the seismic risk in longitudinal direction of high-speed railway multi-span simply-supported beam bridge
The track structure has an effect on the dynamic characteristics of the bridge structure, which makes the seismic response of the bridge structure complicated. In this paper, an assessment method is proposed t...
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Article
Numerical simulation for investigating the impact of shot peening process parameters via surface reconstruction
Shot peening is one of the most widely used surface strengthening processes. The shot peening process involves multiple process parameters, which have a complex and interdependent impact on the peening effects...
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Article
Open AccessConstruction of prediction model for KRAS mutation status of colorectal cancer based on CT radiomics
In this study, we used computed tomography (CT)-based radiomics signatures to predict the mutation status of KRAS in patients with colorectal cancer (CRC) and to identify the phase of radiomics signature with the...
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Article
A novel 3D printed technology to construct a monolithic ultrathin nanosheets Co3O4/SiO2 catalyst for benzene catalytic combustion
In this study, a novel three-dimensional (3D)-OMm-Co3O4/SiO2-0.5AP (OMm = ordered macro–meso porous, AP = aluminum phosphate) monolithic catalyst was for the first time constructed successfully with the hierarchi...
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Article
Seismic applicability analysis of high-speed railway multi-span simply-supported bridges based on simplified model
CRTS II ballastless track is more commonly used in railway operations since it can meet the railway comfort and smoothness requirements. The effects of track constraint on the seismic response of high-speed ra...
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Article
Open AccessDifferentiation of retroperitoneal paragangliomas and schwannomas based on computed tomography radiomics
The purpose of this study was to differentiate the retroperitoneal paragangliomas and schwannomas using computed tomography (CT) radiomics. This study included 112 patients from two centers who pathologically ...
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Article
Open AccessEffects of pre-operative oral carbohydrates on insulin resistance and postoperative recovery in diabetic patients undergoing coronary artery bypass grafting: study protocol for a prospective, single-blind, randomized controlled trial
Preoperative carbohydrates (CHO) supplement has been widely investigated in nondiabetic patients undergoing a variety of surgeries. It has been proved that preoperative CHO could alleviate postoperative insuli...
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Article
Open AccessNomogram based on MRI can preoperatively predict brain invasion in meningioma
Predicting brain invasion preoperatively should help to guide surgical decision-making and aid the prediction of meningioma grading and prognosis. However, only a few imaging features have been identified to a...
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Article
A ratiometric fluorescence method based on nitrogen-doped carbon quantum dots for the determination of the activity of alkaline phosphatase
Herein, a simple and sensitive ratiometric fluorescence sensing platform to detect alkaline phosphatase (ALP) activity is developed on the basis of yellow fluorescent nitrogen-doped carbon quantum dots (YNCDs)...
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Article
RDIVpSGP motif of ASPP2 binds to 14-3-3 and enhances ASPP2/k18/14-3-3 ternary complex formulation to promote BRAF/MEK/ERK signal inhibited cell proliferation in hepatocellular carcinoma
The Apoptosis Stimulating Protein of p53 2 (ASPP2) is a heterozygous insufficient tumor suppressor; however, its molecular mechanism(s) in tumor suppression is not completely understood. ASPP2 plays an essenti...
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Article
Control of Difference of Seismic Response across Different Spans of high-speed railway multi-spans simply supported bridge
In this paper, the Difference of Seismic Response across Different Spans (DSR) in the longitudinal distribution of High-Speed Railway Multi-spans Simply Supported Bridge (HSRSB) under longitudinal earthquake e...
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Article
Effects of near-fault pulse-type ground motions on high-speed railway simply supported bridge and pulse parameter analysis
Based on an innovative high-speed railway simply supported bridge (HSRSSB) model, the potential influence of near-fault pulse-type ground motions on HSRSSB is analyzed. Eighty-five original records of such gro...
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Article
Dynamic response analysis of a multiple-beam structure subjected to a moving load
In this study, the dynamic response of an elastically connected multi-beam structure subjected to a moving load with elastic boundary conditions is investigated. The boundary conditions and properties of each ...
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Article
Open AccessHeterogeneity induced GZMA-F2R communication inefficient impairs antitumor immunotherapy of PD-1 mAb through JAK2/STAT1 signal suppression in hepatocellular carcinoma
Tumor heterogeneity has been associated with immunotherapy and targeted drug resistance in hepatocellular carcinoma (HCC). However, communications between tumor and cytotoxic cells are poorly understood to dat...
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Article
Comparative analysis of magnetic resonance imaging and pathological findings of microcystic meningioma and meningeal Ewing sarcoma/peripheral primitive neuroectodermal tumors
Microcystic meningiomas (MCMs) and meningeal Ewing sarcoma/peripheral primitive neuroectodermal tumours (pPNETs) are difficult to differentiate because of the similarity in their image manifestation on magneti...
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Article
Running test on high-speed railway track-simply supported girder bridge systems under seismic action
Considering that existing shaking table tests on bridge structures have not taken into account the effect of moving trains, this paper takes a multi-span simply supported girder with a CRTSII slab ballastless ...
