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  1. Article

    Open Access

    Role of liver FGF21-KLB signaling in ketogenic diet-induced amelioration of hepatic steatosis

    The effectiveness of ketogenic diet (KD) in ameliorating fatty liver has been established, although its mechanism is under investigation. Fibroblast growth factor 21 (FGF21) positively regulates obesity-associ...

    Wanrong Guo, Huanyi Cao, Yunfeng Shen, Wuguo Li, Wei Wang… in Nutrition & Diabetes (2024)

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  2. Article

    Open Access

    HbA1c is a predictive factor of severe coronary stenosis and major adverse cardiovascular events in patients with both type 2 diabetes and coronary heart disease

    Coronary heart disease (CHD) is not only a macrovascular complication of type 2 diabetes mellitus (T2DM). Cardiovascular disease (CVD) is one of the leading causes of mortality among individuals with T2DM. Red...

    **aojuan Jiao, Qin Zhang, ** Peng, Yunfeng Shen in Diabetology & Metabolic Syndrome (2023)

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  3. No Access

    Article

    Insight into the biochemical characteristics of a novel glucokinase gene mutation

    Glucokinase (GCK) acts as a glucose sensor and regulates β-cell insulin secretion. The heterozygous mutations in the gene encoding GCK cause a reduction of the enzyme activity, which results in a monogenic for...

    Yunfeng Shen, Mengyin Cai, Hua Liang, Hongwei Wang, Jian** Weng in Human Genetics (2011)