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    Insight into the biochemical characteristics of a novel glucokinase gene mutation

    Glucokinase (GCK) acts as a glucose sensor and regulates β-cell insulin secretion. The heterozygous mutations in the gene encoding GCK cause a reduction of the enzyme activity, which results in a monogenic for...

    Yunfeng Shen, Mengyin Cai, Hua Liang, Hongwei Wang, Jian** Weng in Human Genetics (2011)