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SUMOylation of PDPK1 Is required to maintain glycolysis-dependent CD4 T-cell homeostasis

The immune system is finely tuned to fight against infections, eradicate neoplasms, and prevent autoimmunity. Protein posttranslational modification (PTM) constitutes a molecular layer of regulation to guarant...

Fei Sun, Fa-** Wang, He Zhu, Tian-Tian Yue, Chun-Liang Yang… in Cell Death & Disease (2022)