3 Result(s)
within
English
Oncology
Yun-Peng Peng
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Article
Open AccessYin Yang-1 suppresses invasion and metastasis of pancreatic ductal adenocarcinoma by downregulating MMP10 in a MUC4/ErbB2/p38/MEF2C-dependent mechanism
Increasing evidence indicates an important role of transcription factor Yin Yang-1 (YY1) in human tumorigenesis. However, its function in cancer remains controversial and the relevance of YY1 to pancreatic duc...
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Article
Open AccessElevation of MMP-9 and IDO induced by pancreatic cancer cells mediates natural killer cell dysfunction
Natural killer (NK) cells play a key role in non-specific immune response in different cancers, including pancreatic cancer. However the anti-tumor effect of NK cells decreases during pancreatic cancer progres...
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Article
Open AccessPEG10 overexpression induced by E2F-1 promotes cell proliferation, migration, and invasion in pancreatic cancer
Overexpression of paternally expressed gene-10 (PEG10) is known to promote the progression of several carcinomas, however, its role in pancreatic cancer (PC) is unknown. We investigated the expression and func...
