Page
%P
-
Article
10,11-dehydrocurvularin exerts antitumor effect against human breast cancer by suppressing STAT3 activation
Aberrant activation of signal transducer and activator of transcription 3 (STAT3) plays a critical role in many types of cancers. As a result, STAT3 has been identified as a potential target for cancer therapy...
-
Article
Pristimerin protects against inflammation and metabolic disorder in mice through inhibition of NLRP3 inflammasome activation
Excessive activation of NLRP3 inflammasome is associated with the pathogenesis of inflammatory diseases. Pristimerin (Pri) is a quinonoid triterpene derived from traditional Chinese medical herb Celastraceae and