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  1. Article

    Open Access

    Pathologically catalyzed physical coating restores the intestinal barrier for inflammatory bowel disease therapy

    Intestinal epithelia impairment of inflammatory bowel disease (IBD) leads to the leakage of bacteria and antigens and the consequent persistent immune imbalance. Restoring the epithelial barrier is a promising...

    Yuge Zhao, Ruiqing He, Jie Zang, Weimin Yin, Run** Su in Journal of Nanobiotechnology (2023)

  2. Article

    Open Access

    CaCO3 powder-mediated biomineralization of antigen nanosponges synergize with PD-1 blockade to potentiate anti-tumor immunity

    Antigen self-assembly nanovaccines advance the minimalist design of therapeutic cancer vaccines, but the issue of inefficient cross-presentation has not yet been fully addressed. Herein, we report a unique app...

    Run** Su, **g**g Gu, Juanjuan Sun, Jie Zang, Yuge Zhao in Journal of Nanobiotechnology (2023)

  3. Article

    Open Access

    “Two-birds-one-stone” colon-targeted nanomedicine treats ulcerative colitis via remodeling immune microenvironment and anti-fibrosis

    Dysregulated mucosal immune responses and colonic fibrosis impose two formidable challenges for ulcerative colitis treatment. It indicates that monotherapy could not sufficiently deal with this complicated dis...

    Jiaxin Zhang, Ante Ou, Xue** Tang, Rong Wang, Yujuan Fan in Journal of Nanobiotechnology (2022)

  4. Article

    Open Access

    Nanofactory for metabolic and chemodynamic therapy: pro-tumor lactate trap** and anti-tumor ROS transition

    Lactate plays a critical role in tumorigenesis, invasion and metastasis. Exhausting lactate in tumors holds great promise for the reversal of the immunosuppressive tumor microenvironment (TME). Herein, we repo...

    Ruiqing He, Jie Zang, Yuge Zhao, Ying Liu, Shuangrong Ruan in Journal of Nanobiotechnology (2021)