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Article
Open AccessPathologically catalyzed physical coating restores the intestinal barrier for inflammatory bowel disease therapy
Intestinal epithelia impairment of inflammatory bowel disease (IBD) leads to the leakage of bacteria and antigens and the consequent persistent immune imbalance. Restoring the epithelial barrier is a promising...
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Article
Model optimization of English intelligent translation based on outlier detection and machine learning
With the actual demand of international communication, intelligent translation of English has become a key direction of artificial intelligence development in the current English field. For the existing Englis...
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Article
Native and engineered exosomes for inflammatory disease
Exosomes are extracellular vesicles which carry specific molecular information from donor cells and act as an intercellular communication vehicle, which have emerged as a novel cell-free strategy for the treat...
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Article
Open AccessCaCO3 powder-mediated biomineralization of antigen nanosponges synergize with PD-1 blockade to potentiate anti-tumor immunity
Antigen self-assembly nanovaccines advance the minimalist design of therapeutic cancer vaccines, but the issue of inefficient cross-presentation has not yet been fully addressed. Herein, we report a unique app...
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Article
Open Access“Two-birds-one-stone” colon-targeted nanomedicine treats ulcerative colitis via remodeling immune microenvironment and anti-fibrosis
Dysregulated mucosal immune responses and colonic fibrosis impose two formidable challenges for ulcerative colitis treatment. It indicates that monotherapy could not sufficiently deal with this complicated dis...
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Article
Open AccessNanofactory for metabolic and chemodynamic therapy: pro-tumor lactate trap** and anti-tumor ROS transition
Lactate plays a critical role in tumorigenesis, invasion and metastasis. Exhausting lactate in tumors holds great promise for the reversal of the immunosuppressive tumor microenvironment (TME). Herein, we repo...
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Article
Hierarchically porous carbon from foamed Mg chelate for supercapacitor and capacitive deionization
Pore hierarchy facilitates the mass transportation/exchange between the interior surface and bulk solution, which is critical for the enhancement of capacitive performance. Herein, by applying in situ foamed M...
