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Article

The TAK1-JNK cascade is required for IRF3 function in the innate immune response

Interferon regulatory factor (IRF)3 is critical for the transcriptional induction of chemokines and cytokines during viral or bacterial invasion. The kinases Tank binding kinase (TBK)1 and Ikappa B kinase (IKK...

Bianhong Zhang, Meng Li, Liang Chen, Kai Yang, Yufei Shan, Lianhui Zhu… in Cell Research (2009)