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Article
Asymmetric catalytic synthesis of chiral covalent organic framework composite (S)-DTP-COF@SiO2 for HPLC enantioseparations by normal-phase and reversed-phase chromatographic modes
A novel CCOF core–shell composite material (S)-DTP-COF@SiO2 was prepared via asymmetric catalytic and in situ growth strategy. The prepared (S)-DTP-COF@SiO2 was utilized as separation medium for HPLC enantiosepar...
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Article
Bismuth-Containing Quadruple Therapy for Helicobacter pylori Eradication: A Randomized Clinical Trial of 10 and 14 Days
Bismuth-containing quadruple therapy is the first-line treatment for eradicating Helicobacter pylori (H. pylori). The optimal duration for H. pylori eradication using bismuth-containing quadruple therapy remains ...
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Article
Open AccessUse of dual genomic sequencing to screen mitochondrial diseases in pediatrics: a retrospective analysis
Mitochondrial diseases (MDs) were a large group multisystem disorders, attributable in part to the dual genomic control. The advent of massively sequencing has improved diagnostic rates and speed, and was incr...
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Article
Silica-confined composite form-stable phase change materials: a review
Solid–liquid phase change materials (PCMs) are a kind of important heat energy storage materials that can store/release great amounts of latent heat at a specific temperature or within a narrow temperature ran...
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Article
Itaconate inhibits TET DNA dioxygenases to dampen inflammatory responses
As one of the most induced genes in activated macrophages, immune-responsive gene 1 (IRG1) encodes a mitochondrial metabolic enzyme catalysing the production of itaconic acid (ITA). Although ITA has an anti-infla...
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Article
Open AccessInterleukin-37 promotes colitis-associated carcinogenesis via SIGIRR-mediated cytotoxic T cells dysfunction
Interleukin-37b (hereafter called IL-37) was identified as fundamental inhibitor of natural and acquired immunity. The molecular mechanism and function of IL-37 in colorectal cancer (CRC) has been elusive. Her...
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Article
Open AccessLeopard syndrome: the potential cardiac defect underlying skin phenotypes
LEOPARD syndrome (OMIM #151,100) caused by a germline PTPN11 mutation are characterized as multisystemic anomalies and variable marked phenotypes such as multiple lentigines and cafe´-au-lait spots, electrocar...
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Article
Open AccessDiagnostic performance of individual characteristics and anthropometric measurements in detecting elevated serum alanine aminotransferase among children and adolescents
Screening for elevated serum alanine aminotransferase (ALAT) can help identifying individuals at the risks of chronic and metabolic diseases, but blood collection is invasive and cannot be widely used for inve...
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Article
Clinical observation of treatment of infantile diarrhea due to spleen deficiency using five-step pediatric tuina of Huxiang school
Objective: To observe the clinical efficacy of treating infantile diarrhea due to spleen deficiency with five-step pediatric tuina of Huxiang school.
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Article
Open AccessHIV prevalence in suspected Ebola cases during the 2014–2016 Ebola epidemic in Sierra Leone
The 2014–2016 Ebola virus epidemic in West Africa was the largest outbreak of Ebola virus disease (EVD) in history. Clarifying the influence of other prevalent diseases such as human immunodeficiency virus inf...
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Article
Clinical Efficacy and Safety of Bathing with Chinese Medicine Taohong Siwu Decoction (桃红四物汤) for Treatment of Diffuse Cutaneous Systemic Sclerosis: A Randomized Placebo-Controlled Trial
To examine the efficacy and safety of bathing therapy with Taohong Siwu Decoction (桃红四物汤, TSD) in the treatment of early-stage, mild-moderate diffuse cutaneous systemic sclerosis (dcSSc).
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Article
Effects of some nucleating agents on the supercooling of erythritol to be applied as phase change material
Nine nucleating agents, calcium pimelate (CaPi), bicyclic [1, 2, 2]heptane di-carboxylate (HPN-68), a commercially obtained aryl amide nucleating agent (TMB-5), calcium salt of hexahydrophthalic acid (HPN-20E)...
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Article
Open AccessSuppression of diabetic retinopathy with GLUT1 siRNA
To investigate the effect of glucose transporter-1 (GLUT1) inhibition on diabetic retinopathy, we divided forty-eight mice into scrambled siRNA, diabetic scrambled siRNA, and GLUT1 siRNA (intravitreally inject...
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Article
The opioid receptor triple agonist DPI-125 produces analgesia with less respiratory depression and reduced abuse liability
Opioid analgesics remain the first choice for the treatment of moderate to severe pain, but they are also notorious for their respiratory depression and addictive effects. This study focused on the pharmacolog...
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Article
A scintillator detector for beam tuning of low-energy single electron accelerator
Nine scintillator detectors were developed for beam tuning of low-energy single electron accelerator instead of the picoammeter and Faraday cup, both of which will be insensitive to the weak-current beam lower...
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Article
Open AccessPrevalence of metabolic syndrome and its risk factors among rural adults in Nantong, China
The prevalence of metabolic syndrome (MS) varies worldwide due to genetic and environmental factors. A population-based cross-sectional study, with 37,582 participants recruited in Nantong, China in 2007-2008 ...
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Article
Open AccessErratum to: Effects of dietary supplementation of golden apple snail (Pomacea canaliculata) egg on survival, pigmentation and antioxidant activity of Blood parrot
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Article
Open AccessEffects of dietary supplementation of golden apple snail (Pomacea canaliculata) egg on survival, pigmentation and antioxidant activity of Blood parrot
This study aims to evaluate the effects of supplementing golden apple snail (Pomacea canaliculata) eggs powder (EP) in the diet as a source of natural carotenoids on survival, pigmentation and antioxidant activit...
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Article
The application of CT voiding urethrography in the evaluation of urethral stricture associated with fistula: a preliminary report
This study was designed to evaluate the clinical utility of CT voiding urethrography (2D/3D reformatted CT images and virtual cystourethroscopy) in terms of its ability to detect urethral stricture associated ...
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Article
Coordination architectures of copper(II) coordination polymers constructed from bifunctional 5-substituted-tetrazole-carboxylate ligands
Three complexes of the bifunctional 5-substituted-tetrazolate-carboxylate ligands 3-(5-amino-2H-tetrazol-1(5H)-yl) propanoic acid (Hatzp), 5-(2-pyrimidyl)tetrazole-1-acetic acid (Hpymtza) and 1H-tetrazolate-5...
