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6 Result(s)

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  1. No Access

    Article

    Antitumor effects of the flavone chalcone: inhibition of invasion and migration through the FAK/JNK signaling pathway in human gastric adenocarcinoma AGS cells

    Chalcones (benzylideneacetophenone) are cancer-preventive food components found in a human diet rich in fruits and vegetables. In this study, we first report the chemopreventive effect of chalcone in human gas...

    Su-Hsuan Lin, Yuan-Wei Shih in Molecular and Cellular Biochemistry (2014)

  2. No Access

    Article

    Acacetin inhibits the invasion and migration of human non-small cell lung cancer A549 cells by suppressing the p38α MAPK signaling pathway

    Lung cancer is one of the most common malignancies in the world and its metastasis is the major cause of death in cancer patients. Acacetin (5,7-dihydroxy-4′-methoxyflavone), a flavonoid compound, has anti-per...

    Shang-Tao Chien, Su-Shun Lin, Cheng-Kun Wang… in Molecular and Cellular Biochemistry (2011)

  3. No Access

    Article

    Nobiletin, a citrus flavonoid, suppresses invasion and migration involving FAK/PI3K/Akt and small GTPase signals in human gastric adenocarcinoma AGS cells

    Nobiletin, a compound isolated from citrus fruits, is a polymethoxylated flavone derivative shown to have anti-inflammatory, antitumor, and neuroprotective properties. This study has investigated that nobileti...

    Yi-Chieh Lee, Tsan-Hwang Cheng, Jung-Shin Lee… in Molecular and Cellular Biochemistry (2011)

  4. No Access

    Article

    Plumbagin inhibits TPA-induced MMP-2 and u-PA expressions by reducing binding activities of NF-κB and AP-1 via ERK signaling pathway in A549 human lung cancer cells

    This study first investigates the anti-metastatic effect of plumbagin (5-hydroxy-2-methyl-1,4-naphthoquinone) on 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced MMPs and u-PA expressions in human lung cancer c...

    Jiunn-Min Shieh, Tai-An Chiang, Wen-Teng Chang… in Molecular and Cellular Biochemistry (2010)

  5. No Access

    Article

    Acacetin, a flavonoid, inhibits the invasion and migration of human prostate cancer DU145 cells via inactivation of the p38 MAPK signaling pathway

    Acacetin (5,7-dihydroxy-4′-methoxyflavone), a flavonoid compound, has anti-peroxidative and anti-inflammatory effects. The effect of acacetin on antimetastasis in human prostate cancer DU-145 cells was investi...

    Kun-Hung Shen, Shun-Hsing Hung, Li-Te Yin… in Molecular and Cellular Biochemistry (2010)

  6. No Access

    Article

    Antimetastatic potential of fisetin involves inactivation of the PI3K/Akt and JNK signaling pathways with downregulation of MMP-2/9 expressions in prostate cancer PC-3 cells

    Fisetin (3,3′,4′,7-tetrahydroxyflavone), a naturally occurring flavonoid, has been reported to possess some anti-cancer and anti-inflammation capabilities. In this study, fisetin has exhibited inhibitory effec...

    Chi-Sheng Chien, Kun-Hung Shen, Jau-Shyang Huang… in Molecular and Cellular Biochemistry (2010)