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Open AccessDevelopment of a perfusion process for serum-free adenovirus vector herpes zoster vaccine production
Herpes zoster is caused by reactivation of the varicella zoster virus (VZV). Researching and develo** a herpes zoster vaccine will help to decrease the incidence of herpes zoster. To increase the bioreactor ...
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Article
Open AccessSpoVG is an important regulator of sporulation and affects biofilm formation by regulating Spo0A transcription in Bacillus cereus 0–9
Bacillus cereus 0–9, a Gram-positive, endospore-forming bacterium isolated from healthy wheat roots in our previous research, is considered to be an effective biocontrol strain against several soil-borne plant di...
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Article
Composable microfluidic spinning platforms for facile production of biomimetic perfusable hydrogel microtubes
Microtissues with specific structures and integrated vessels play a key role in maintaining organ functions. To recapitulate the in vivo environment for tissue engineering and organ-on-a-chip purposes, it is e...
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Article
Characterizing three dimensional (3-D) morphology of residential buildings by landscape metrics
The key attributes of landscape pattern include composition and configuration, which can be depicted by landscape/spatial metrics. An emerging pathway is leveraging vertical data to advance three-dimensional (...
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Article
Impacts of landscape changes on local and regional climate: a systematic review
Studies have shown that land use and land cover change (LUCC) has myriad impacts on local and regional climate. Synthesizing the recent findings in this field helps advance landscape ecology and sustainability...
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Article
Open AccessConserved Pbp1/Ataxin-2 regulates retrotransposon activity and connects polyglutamine expansion-driven protein aggregation to lifespan-controlling rDNA repeats
Ribosomal DNA (rDNA) repeat instability and protein aggregation are thought to be two major and independent drivers of cellular aging. Pbp1, the yeast ortholog of human ATXN2, maintains rDNA repeat stability a...
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Article
Circulating Tumor Cells (CTCs) Detected by Triple-Marker EpCAM, CK19, and hMAM RT-PCR and Their Relation to Clinical Outcome in Metastatic Breast Cancer Patients
In order to investigate the prognostic value of circulating tumor cells (CTCs) in patients with metastatic breast cancer (MBC), the blood cells from 98 MBC patients and 60 controls were evaluated by RT-PCR to ...