6 Result(s)
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Article
Open AccessSurface-confined alternating copolymerization with molecular precision by stoichiometric control
Keen desires for artificial mimicry of biological polymers and property improvement of synthesized ones have triggered intensive explorations for sequence-controlled copolymerization. However, conventional syn...
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Article
Open AccessYBX1 integration of oncogenic PI3K/mTOR signalling regulates the fitness of malignant epithelial cells
In heterogeneous head and neck cancer (HNC), subtype-specific treatment regimens are currently missing. An integrated analysis of patient HNC subtypes using single-cell sequencing and proteome profiles reveals...
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Article
Open AccessReconstruction of full-length ureter defects by laparoscopic bladder flap forming
To evaluate the safety and efficacy of laparoscopic bladder muscle flap reconstruction in the treatment of extensive ureteral avulsion. Patients with full-length (re length > 20 cm) and upper ureteral (avulsi...
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Article
Open AccessA primer set for the rapid isolation of scFv fragments against cell surface antigens from immunised rats
Antibody phage display is a powerful platform for discovery of clinically applicable high affinity monoclonal antibodies against a broad range of targets. Libraries generated from immunized animals offer the a...
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Article
Open AccessComprehensive epigenetic landscape of rheumatoid arthritis fibroblast-like synoviocytes
Epigenetics contributes to the pathogenesis of immune-mediated diseases like rheumatoid arthritis (RA). Here we show the first comprehensive epigenomic characterization of RA fibroblast-like synoviocytes (FLS)...
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Article
Open AccessThe prognostic significance of Cdc6 and Cdt1 in breast cancer
DNA replication is a critical step in cell proliferation. Overexpression of MCM2-7 genes correlated with poor prognosis in breast cancer patients. However, the roles of Cdc6 and Cdt1, which work with MCMs to r...
