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Article
Role of automated functional imaging and myocardial work in assessment of cardiac function in children with obstructive sleep apnea
Early identification of abnormal left ventricular function in children with obstructive sleep apnea (OSA) is difficult using conventional echocardiographic indices and commonly used clinical markers of myocard...
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Article
Open AccessReal-world efficacy and safety of TACE plus camrelizumab and apatinib in patients with HCC (CHANCE2211): a propensity score matching study
This study aimed to investigate the efficacy and safety of transarterial chemoembolization (TACE) plus camrelizumab, a monoclonal antibody targeting programmed death-1, and apatinib for patients with intermedi...
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Article
Iodine status and associated dietary factors among preschool children in Shanghai
Children aged 3–6 years undergo a critical stage of growth and development and are irreversibly affected by their iodine status. In order to reveal iodine status in preschool children, we detected iodine conce...
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Article
Determinants affecting the blood mercury levels of preschool children in Shanghai, China: A cross-sectional study
Infants and children are vulnerable to mercury (Hg)-induced toxicity, which has detrimental effects on their neurological development. This study measured blood Hg levels (BMLs) and identified potential factor...
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Article
Study of nonequilibrium phase transitions mechanisms in exclusive network and node model of heterogeneous assignment based on real experimental data of KIF3AC and KIF3CC motors
By simulating nonequilibrium processes like biological transport, traffic transport, etc., totally asymmetric simple exclusion process (i.e., TASEP) is vital to understand stochastic dynamics of lattice system...
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Article
2022 roadmap on hydrogen energy from production to utilizations
Hydrogen has been always the hot topic, which drives a lot of researchers to study and explore hydrogen-related projects and fields. The first subfield is hydrogen production with green and cost-effective mean...
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Article
Nonequilibrium phase transitions in a two-channel ASEP with binding energies and analytical evaluations via Kullback–Leibler divergence
In order to reflect new physical insights in understanding nonequilibrium phase transition mechanisms of real mesoscopic transport, a new exclusion process with horizontal and vertical binding energies is cons...
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Article
Identification of pimavanserin tartrate as a potent Ca2+-calcineurin-NFAT pathway inhibitor for glioblastoma therapy
Glioblastoma multiforme (GBM) is the most common and malignant type of primary brain tumor, and 95% of patients die within 2 years after diagnosis. In this study, aiming to overcome chemoresistance to the firs...
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Article
Open AccessLarval metamorphosis is inhibited by methimazole and propylthiouracil that reveals possible hormonal action in the mussel Mytilus coruscus
Larval metamorphosis in bivalves is a key event for the larva-to-juvenile transformation. Previously we have identified a thyroid hormone receptor (TR) gene that is crucial for larvae to acquire “competence” f...
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Article
Phase transitions in two-channel TASEPs based on a new method of cluster mean-field analyses
A molecular motor transport model which is much closer to the actual situation is studied in this work. The two-chain totally asymmetric simple exclusion process (TASEP) with transverse and longitudinal bindin...
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Article
Cluster dynamics in the open-boundary heterogeneous ASEPs coupled with interacting energies
Cluster dynamics possess the promising studies in statistical physics and complexity science. While proposing physical models, applying analytical methods and exploring macroscopic properties and microscopic i...
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Article
Open AccessAnalytical and simulation studies of driven diffusive system with asymmetric heterogeneous interactions
Totally asymmetric simple exclusion process (namely, TASEP) is one of the most vital driven diffusive systems, which depicts stochastic dynamics of self-driven particles unidirectional updating along one-dimen...
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Article
Preserving privacy information flow security in composite service evolution
After a composite service is deployed, user privacy requirements and trust levels of component services are subject to variation. When the changes occur, it is critical to preserve privacy information flow sec...
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Article
Open AccessStructure-Activity Relationship Studies of β-Lactam-azide Analogues as Orally Active Antitumor Agents Targeting the Tubulin Colchicine Site
We have synthesized a series of new β-lactam-azide derivatives as orally active anti-tumor agents by targeting tubulin colchicine binding site and examined their structure activity relationship (SAR). Among them,...
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Article
Dynamics in phase transitions of TASEP coupled with multi-lane SEPs
In this paper, we study a traffic model constituted by totally asymmetric simple exclusion process (TASEP) and two-lane simple exclusion processes (SEP). Then we generalize it to study TASEP coupled with multi...
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Article
Dynamics in multi-lane TASEPs coupled with asymmetric lane-changing rates
The paper studies periodic two-dimensional exclusion processes constituted by multi-lane totally asymmetric simple exclusion processes with the effect of asymmetric lane-changing rates. Particles in lane i can mo...
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Article
DLPlib: A Library for Deep Learning Processor
Recently, deep learning processors have become one of the most promising solutions of accelerating deep learning algorithms. Currently, the only method of programming the deep learning processors is through wr...
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Article
Norepinephrine induced epithelial–mesenchymal transition in HT-29 and A549 cells in vitro
Norepinephrine (NE) has been implicated in epithelial–mesenchymal transition (EMT) of cancer cells. However, the underlying mechanism is poorly understood. The goal of this study was to explore the effect of N...
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Article
Semi-quantitative determination of monocarboxylate forms of ginkgolide B in plasma by UPLC-MS
Ginkgolide B (GB) has a unique structure incorporating three γ-lactones that may be hydrolyzed in aquae as carboxylate forms. However, the determinations of them are challenging because there is no way to prep...
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Article
Erratum: Tet1-mediated DNA demethylation regulates neuronal cell death induced by oxidative stress
Epigenetic regulations including DNA methylation and demethylation play critical roles in neural development. However, whether DNA methylation and demethylation may play a role in neuronal cell death remains l...
