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  1. Article

    Open Access

    Fis1 phosphorylation by Met promotes mitochondrial fission and hepatocellular carcinoma metastasis

    Met tyrosine kinase, a receptor for a hepatocyte growth factor (HGF), plays a critical role in tumor growth, metastasis, and drug resistance. Mitochondria are highly dynamic and undergo fission and fusion to m...

    Yan Yu, **ao-Dan Peng, **ao-Jun Qian in Signal Transduction and Targeted Therapy (2021)

  2. Article

    Open Access

    The sirtuin family in health and disease

    Sirtuins (SIRTs) are nicotine adenine dinucleotide(+)-dependent histone deacetylases regulating critical signaling pathways in prokaryotes and eukaryotes, and are involved in numerous biological processes. Cur...

    Qi-Jun Wu, Tie-Ning Zhang, Huan-Huan Chen in Signal Transduction and Targeted Therapy (2022)

  3. Article

    Open Access

    Metatranscriptome of human lung microbial communities in a cohort of mechanically ventilated COVID-19 Omicron patients

    The Omicron variant of the severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) infected a substantial proportion of Chinese population, and understanding the factors underlying the severity of the dis...

    Lin Wang, Jia-Bao Cao, Bin-Bin **a, Yue-Juan Li in Signal Transduction and Targeted Therapy (2023)