42 Result(s)

Article

Integrated analysis of intratumoral biomarker and tumor-associated macrophage to improve the prognosis prediction in cancer patients

The lack of effective and accurate predictive indicators remains a major bottleneck for the improvement of the prognosis of patients with hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC). Hepatit...

Ming-Da Wang, Hao **ang, Tian-Yu Hong, Abudurexiti Mierxiati, Fei-Hu Yan… in BMC Cancer (2023)

Article

Clonal relationship and alcohol consumption-associated mutational signature in synchronous hypopharyngeal tumours and oesophageal squamous cell carcinoma

The patients with dual oesophageal squamous cell carcinoma (ESCC) and hypopharyngeal cancer (HPC) have poor prognosis; their underlying genetic pathogenesis is unclear. We hypothesise that development of synch...

Josephine Mun-Yee Ko, Chen Guo, Conghui Liu, Lvwen Ning… in British Journal of Cancer (2022)

Article

Comparison of response evaluation criteria in solid tumors and tumor regression grade in evaluating the effect of preoperative systemic therapy of gastric cancer

Both Response Evaluation Criteria in Solid Tumors (RECIST) and tumor regression grade (TRG) play key roles in evaluating tumor response. We analyzed the consistency of TRG and RECIST 1.1 for gastric cancer (GC...

Ming-Yu Lai, Shi-Yang Kang, Yu-Ting Sun, Ting-Ting Quan, Shi-Xun Lu… in BMC Cancer (2022)

Article

Comparison of radiotherapy combined with nimotuzumab vs. chemoradiotherapy for locally recurrent nasopharyngeal carcinoma

The present study compared the effectiveness and toxicity of two treatment modalities, namely radiotherapy combined with nimotuzumab (N) and chemoradiotherapy (CRT) in patients with locally recurrent nasophary...

**g-Feng Zong, Qian-Dong Liang, Qiong-Jiao Lu, Yu-Hong Liu, Han-Chuan Xu… in BMC Cancer (2021)

Article

Pathological and genomic phenotype of second neuroendocrine carcinoma during long-term follow-up after radical radiotherapy for nasopharyngeal carcinoma

Second head and neck neuroendocrine carcinoma (NEC) after radical radiotherapy for nasopharyngeal carcinoma (NPC) treatment is rarely reported. The prognosis of second cancer is poor, and our research focuses ...

Ying-peng Peng, Qiao-dan Liu, Yu-**g Lin, Shun-li Peng, Rong Wang… in Radiation Oncology (2021)

Article

Correction to: Long non-coding RNA XIST regulates gastric cancer progression by acting as a molecular sponge of miR-101 to modulate EZH2 expression

Dong-liang Chen, Huai-qiang Ju, Yun-xin Lu… in Journal of Experimental & Clinical Cancer … (2021)

Article

Wilms’ tumor gene 1 is an independent prognostic factor for pediatric acute myeloid leukemia following allogeneic hematopoietic stem cell transplantation

Sequential monitoring of Wilms’ tumor gene 1 (WT1) after allogeneic hematopoietic stem cell transplantation (allo-HSCT) could predict relapse in adult acute myeloid leukemia (AML). However, the prognostic role...

Dao-**ng Deng, Juan-Juan Wen, Yi-Fei Cheng, **ao-Hui Zhang, Lan-** Xu… in BMC Cancer (2021)

Article

The predicting role of circulating tumor DNA landscape in gastric cancer patients treated with immune checkpoint inhibitors

A more common and noninvasive predicting biomarker for programmed cell death 1 (PD-1) antibody remains to be explored. We assessed 46 patients with advanced gastric cancer who received PD-1 antibody immunother...

Ying **, Dong-Liang Chen, Feng Wang, Chao-pin Yang, Xu-**an Chen… in Molecular Cancer (2020)

Article

Disruption of super-enhancer-driven tumor suppressor gene RCAN1.4 expression promotes the malignancy of breast carcinoma

Super-enhancers (SEs) play a crucial role in cancer, which is often associate with activated oncogenes. However, little is known about how SEs facilitate tumour suppression. Individuals with Down syndrome exhi...

Rong Deng, Jun-Hao Huang, Yan Wang, Li-Huan Zhou, Zi-Feng Wang… in Molecular Cancer (2020)

Article

Allogeneic hematopoietic stem cell transplantation can improve the prognosis of high-risk pediatric t(8;21) acute myeloid leukemia in first remission based on MRD-guided treatment

Pediatric acute myeloid leukemia (AML) with t(8;21) (q22;q22) is classified as a low-risk group. However, relapse is still the main factor affecting survival. We aimed to investigate the effect of allogeneic h...

Guan-hua Hu, Yi-fei Cheng, Ai-dong Lu, Yu Wang, Ying-xi Zuo, Chen-hua Yan… in BMC Cancer (2020)

Article

Phase I study of high-dose ascorbic acid with mFOLFOX6 or FOLFIRI in patients with metastatic colorectal cancer or gastric cancer

Preclinical studies suggest synergistic effectiveness of ascorbic acid (AA, vitamin C) and cytotoxic agents in gastrointestinal malignancies. This phase 1 study aimed to establish the maximum tolerated dose (M...

Feng Wang, Ming-Ming He, Zi-**an Wang, Su Li, Ying **, Chao Ren, Si-Mei Shi… in BMC Cancer (2019)

Article

The efficacy and safety of modified FOLFIRINOX as first-line chemotherapy for Chinese patients with metastatic pancreatic cancer

Oxaliplatin, irinotecan, 5-fluorouracil, and l-leucovorin (FOLFIRINOX) has become one of the first-line treatment options for advanced pancreatic cancer (PC). However, the relatively high rate of grade 3 or 4 adv...

Zhi-Qiang Wang, Fei Zhang, Ting Deng, Le Zhang, Fen Feng… in Cancer Communications (2019)

Article

Risk factors affecting prognosis in metachronous liver metastases from WHO classification G1 and G2 gastroenteropancreatic neuroendocrine tumors after initial R0 surgical resection

Here we describe the treatments and prognosis for metachronous metastases from gastroenteropancreatic neuroendocrine tumors (GEP-NETs) after initial R0 surgical resection at a large center in China.

Yang Lv, Xu Han, Xue-Feng Xu, Yuan Ji, Yu-Hong Zhou, Hui-Chuan Sun, Jian Zhou… in BMC Cancer (2019)

Article

Risk factors to identify patients who may not benefit from whole brain irradiation for brain metastases - a single institution analysis

Radiotherapy plays a major role in the management of brain metastases. This study aimed to identify the subset of patients with multiple brain metastases who may not benefit from whole brain irradiation (WBI) ...

Rebecca Buecker, Zhen-Yu Hong, **ao-Mei Liu, Gert Jaenke, ** Lu… in Radiation Oncology (2019)

Article

Pathologic response after preoperative therapy predicts prognosis of Chinese colorectal cancer patients with liver metastases

Pathologic response is evaluated according to the extent of tumor regression and is used to estimate the efficacy of preoperative treatment. Several studies have reported the association between the pathologic...

Yun Wang, Yun-Fei Yuan, Hao-Cheng Lin, Bin-Kui Li… in Chinese Journal of Cancer (2017)

Article

Cdk5 links with DNA damage response and cancer

As an atypical member of cyclin dependent kinase family, Cyclin dependent kinase 5 (Cdk5) is considered as a neuron-specific kinase in the past decade due to the abundant existence of its activator p35 in post...

Wan Liu, Jun Li, Yu-Shu Song, Yue Li, Yu-Hong Jia, Hai-Dong Zhao in Molecular Cancer (2017)

Article

Long non-coding RNA XIST regulates gastric cancer progression by acting as a molecular sponge of miR-101 to modulate EZH2 expression

Long non-coding RNAs (lncRNAs) have emerged as critical regulators of tumor progression. However, the role and molecular mechanism of lncRNA XIST in gastric cancer is still unknown.

Dong-liang Chen, Huai-qiang Ju, Yun-xin Lu… in Journal of Experimental & Clinical Cancer … (2016)

Article

Expert consensus on maintenance treatment for metastatic colorectal cancer in China

The impact of maintenance therapy on progression-free survival and overall survival as well as quality of life of Chinese patients with metastatic colorectal cancer has long been under discussion. Recently, s...

Rui-Hua Xu, Lin Shen, ** Li, Jian-Ming Xu, Feng Bi, Yi Ba… in Chinese Journal of Cancer (2016)