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Article

(D620N) VPS35 causes the impairment of Wnt/β-catenin signaling cascade and mitochondrial dysfunction in a PARK17 knockin mouse model

Patients with familial type 17 of Parkinson’s disease (PARK17) manifest autosomal dominant pattern and late-onset parkinsonian syndromes. Heterozygous (D620N) mutation of vacuolar protein sorting 35 (VPS35) is...

Ching-Chi Chiu, Yi-Hsin Weng, Ying-Zu Huang, Rou-Shayn Chen… in Cell Death & Disease (2020)