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  1. Article

    Open Access

    Correlating Reiff scores with clinical, functional, and prognostic factors: characterizing noncystic fibrosis bronchiectasis severity: validation from a nationwide multicenter study in Taiwan

    Our study aimed to confirm a simplified radiological scoring system, derived from a modified Reiff score, to evaluate its relationship with clinical symptoms and predictive outcomes in Taiwanese patients with ...

    Wen-Chien Cheng, Chia-Ling Chang, Chau-Chyun Sheu in European Journal of Medical Research (2024)

  2. Article

    Open Access

    Construction of a gene model related to the prognosis of patients with gastric cancer receiving immunotherapy and exploration of COX7A1 gene function

    GC is a highly heterogeneous tumor with different responses to immunotherapy, and the positive response depends on the unique interaction between the tumor and the tumor microenvironment (TME). However, the cu...

    Si-yu Wang, Yu-xin Wang, Ao Shen, in European Journal of Medical Research (2024)

  3. Article

    Open Access

    Changes of Mycobacterium tuberculosis specific antigen-stimulated CD27CD38+IFN-γ+CD4+ T cells before and after anti-tuberculosis treatment

    The aim of the study was to investigate whether the expression of CD27CD38+ in interferon (IFN)-γ+CD4+ T cells stimulated by the specific antigen early secreted antigenic target-6 (ESAT-6)/culture filter protein...

    Yong Fang, Yuan Tang, Qiao-**a Luo, Na Wang in European Journal of Medical Research (2024)

  4. Article

    Open Access

    Triosephosphate isomerase 1 may be a risk predictor in laryngeal squamous cell carcinoma: a multi-centered study integrating bulk RNA, single-cell RNA, and protein immunohistochemistry

    Although great progress has been made in anti-cancer therapy, the prognosis of laryngeal squamous cell carcinoma (LSCC) patients remains unsatisfied. Quantities of studies demonstrate that glycolytic reprogram...

    Jian-Di Li, Yi Chen, Shu-Wen **g, Li-Ting Wang in European Journal of Medical Research (2023)

  5. Article

    Open Access

    Association between corrected serum calcium levels after dialysis and post-dialysis fatigue risk: a hospital-based case–control study

    Post-dialysis fatigue (PDF) is an important problem in patients undergoing maintenance hemodialysis (MHD); however, evidence of the association between serum calcium after dialysis and the risk of PDF is limit...

    ** **ao, Zhi-Hong Wang, Yan Lu, Shuang Zhang in European Journal of Medical Research (2023)

  6. Article

    Open Access

    Autophagy impairment in patients with obstructive sleep apnea modulates intermittent hypoxia-induced oxidative stress and cell apoptosis via hypermethylation of the ATG5 gene promoter region

    Autophagy is a catabolic process that recycles damaged organelles and acts as a pro-survival mechanism, but little is known about autophagy dysfunction and epigenetic regulation in patients with obstructive sl...

    Yung-Che Chen, I-Chun Lin, Mao-Chang Su in European Journal of Medical Research (2023)

  7. Article

    Open Access

    An artificial intelligence-enabled ECG algorithm for identifying ventricular premature contraction during sinus rhythm

    Ventricular premature complex (VPC) is a common arrhythmia in clinical practice. VPC could trigger ventricular tachycardia/fibrillation or VPC-induced cardiomyopathy in susceptible patients. Existing screening...

    Sheng-Nan Chang, Yu-Heng Tseng, Jien-Jiun Chen in European Journal of Medical Research (2022)

  8. Article

    Open Access

    Early prediction model for prognosis of patients with hepatitis-B-virus-related acute-on-chronic liver failure received glucocorticoid therapy

    Early prediction for short-term prognosis is essential for the management of hepatitis B virus (HBV)-related acute-on-chronic liver failure (ACLF). In this study, we aim to establish a noninvasive model for pr...

    Shuai Gao, Li-Yan Han, Yu-Chen Fan, Kai Wang in European Journal of Medical Research (2022)

  9. Article

    Open Access

    Systemic immune inflammation index and system inflammation response index are potential biomarkers of atrial fibrillation among the patients presenting with ischemic stroke

    Chronic inflammatory disorders in atrial fibrillation (AF) contribute to the onset of ischemic stroke. Systemic immune inflammation index (SIII) and system inflammation response index (SIRI) are the two novel ...

    Kai-bin Lin, Feng-hua Fan, Ming-qi Cai, Yin Yu in European Journal of Medical Research (2022)

  10. Article

    Open Access

    Inhibitors of IFN gene stimulators (STING) improve intestinal ischemia–reperfusion-induced acute lung injury by activating AMPK signaling

    Acute lung injury (ALI) caused by intestinal ischemia–reperfusion is a life-threatening disease. Interferon gene stimulator (STING) is a cytoplasmic DNA sensor that participates in the initiation of the inflammat...

    Mei Yang, Yu-**a Ma, Ying Zhi, Hai-Bin Wang in European Journal of Medical Research (2022)

  11. Article

    Open Access

    TPPA titer as a new adaptation for early diagnosis of congenital syphilis: a retrospective analysis of observation over three years in Yunnan, China

    Early diagnosis of congenital syphilis (CS) is difficult. This study aimed to determine the serological response discipline of syphilis passive antibody (SPA) in infants born to mothers with syphilis and provi...

    Hong-Mei Wang, Yu-Ye Li, Li-** He, Ying-Kui Cao in European Journal of Medical Research (2019)

  12. Article

    Open Access

    A study on relationship between elderly sarcopenia and inflammatory factors IL-6 and TNF-α

    This report aims to study the relationship between sarcopenia of elderly in community and inflammatory factors IL-6 and TNF-α.

    Ai-Lin Bian, Hui-Ying Hu, Yu-Dong Rong, Jian Wang in European Journal of Medical Research (2017)

  13. Article

    Open Access

    Calorie restriction inhibits ovarian follicle development and follicle loss through activating SIRT1 signaling in mice

    Silent information regulator 2 related enzyme 1 (SIRT1) is one of the key factors in the mechanism of calorie restriction (CR) extending lifespan of animals. The aim of the study is to investigate if CR prolon...

    Wei-Juan Liu, **ng-Mei Zhang, Na Wang in European Journal of Medical Research (2015)

  14. Article

    Open Access

    The effects and mechanism of ginsenoside Rg1 on myocardial remodeling in an animal model of chronic thromboembolic pulmonary hypertension

    Recent studies haveshown that ginsenoside Rg1, extracted from the dry roots of Panax notoginseng as a traditional Asian medicine, plays an anti-fibrosis role in myocardial remodeling. However, the mechanism still...

    Chang-yi Li, Wang Deng, **u-qing Liao, Jia Deng in European Journal of Medical Research (2013)

  15. Article

    Open Access

    Clinical significance of combined detection of human papilloma virus infection and human telomerase RNA component gene amplification in patients with squamous cell carcinoma of the esophagus in northern China

    The aim of the study was to test for human papilloma virus (HPV) infection and human telomerase RNA component (hTERC) gene amplification in tissues derived from esophageal cancer, in esophagus displaying atypi...

    Yu-Feng Wang, **n-Shuai Wang, She-Gan Gao in European Journal of Medical Research (2013)

  16. Article

    Open Access

    Tiny cystine stones in the gallbladder of a patient with cholecystolithiasis complicating acute cholecystitis: a case report

    Cystine stones, the main component of which is cystine, are very common urinary calculi, but are rare in the gall bladder. In animals, there has been only one report of cystine gallstones in tree shrews, and t...

    Tie Qiao, Rui-hong Ma, **ao-bing Luo, Yu-yang Feng in European Journal of Medical Research (2012)