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Article
Preparation of (S)-epichlorohydrin using a novel halohydrin dehalogenase by selective conformation adjustment
Chiral epichlorohydrin (ECH) is an attractive intermediate for chiral pharmaceuticals and chemicals preparation. The asymmetric synthesis of chiral ECH using 1,3-dicholoro-2-propanol (1,3-DCP) catalyzed by a h...
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Article
Open AccessIncreased ONECUT2 induced by Helicobacter pylori promotes gastric cancer cell stemness via an AKT-related pathway
Helicobacter pylori (HP) infection initiates and promotes gastric carcinogenesis. ONECUT2 shows promise for tumor diagnosis, prognosis, and treatment. This study explored ONECUT2’s role and the specific mechanism...
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Article
Open AccessExclusive charmonium production at the electron-ion collider in China
We investigate the exclusive \(J/\psi \) J / ψ
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Article
Open AccessGenetic diversity and prevalence of emerging Rickettsiales in Yunnan Province: a large-scale study
Rickettsia and related diseases have been identified as significant global public health threats. This study involved comprehensive field and systematic investigations of various rickettsial organisms in Yunna...
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Article
Phylogenomics, divergence times and notes of orders in Basidiomycota
Basidiomycota is one of the major phyla in the fungal tree of life. The outline of Basidiomycota provides essential taxonomic information for researchers and workers in mycology. In this study, we present a ti...
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Article
Enhancing coercivity and thermal stability of (Nd,Y)–Fe–B sintered magnets through lamellar structure design
The incorporation of the high-abundance rare-earth element Y in (Nd,Y)–Fe–B sintered magnets offers an opportunity to reduce the cost of permanent magnetic materials, while promoting the balanced usage of rare...
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Article
Open AccessRecent advances in 3D Gaussian splatting
The emergence of 3D Gaussian splatting (3DGS) has greatly accelerated rendering in novel view synthesis. Unlike neural implicit representations like neural radiance fields (NeRFs) that represent a 3D scene wit...
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Article
Prediction of bedload transport inside vegetation canopies with natural morphology
Due to vegetation drag and vegetation-generated turbulence, bedload transport in vegetated channels is more complicated than that in nonvegetated channels. It is challenging to obtain accurate predictions of b...
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Article
Improving customer satisfaction in the hotel industry by fusing multi-source user-generated content: An integration method based on the heuristic-systematic model and evidence theory
Improving customer satisfaction is the key factor in enhancing the core competitiveness of hotels, as higher customer satisfaction can lead to long-term benefits such as a positive reputation, customer loyalty...
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Article
Host preference and mortality caused by the parasitoid Sclerodermus guani on different cerambycid species
Parasitoids of wood borers and bark beetles rarely encounter different host species simultaneously in nature, so whether they exhibit any preferences for particular species, and the relative suitability of dif...
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Article
Open AccessMyricetin mitigates motor disturbance and decreases neuronal ferroptosis in a rat model of Parkinson’s disease
Ferroptosis is an iron-dependent cell death form characterized by reactive oxygen species (ROS) overgeneration and lipid peroxidation. Myricetin, a flavonoid that exists in numerous plants, exhibits potent ant...
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Article
Decreasing mitochondrial fission ameliorates HIF-1α-dependent pathological retinal angiogenesis
Angiogenesis plays a critical role in many pathological processes, including irreversible blindness in eye diseases such as retinopathy of prematurity. Endothelial mitochondria are dynamic organelles that unde...
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Article
Visible-light-driven photocatalysis degradation of antibiotic pollutants by La-doped CeO2 nanorods: synergy of La do** and oxygen vacancy
Elemental do** is an effective strategy to enhance photocatalytic activity and extend the light absorption range of single-component photocatalysts. In this work, a series of La-doped CeO2 nanorods (La-CeO2-x) ...
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Article
Characterization of a pangolin SARS-CoV-2-related virus isolate that uses the human ACE2 receptor
Various SARS-CoV-2-related coronaviruses have been increasingly identified in pangolins, showing a potential threat to humans. Here we report the infectivity and pathogenicity of the SARS-CoV-2-related virus, ...
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Article
Z-scheme Bi4O5Br2/NH2-MIL-125(Ti) heterojunctions enable exceptional visible photocatalytic degradation of organic pollutant
One key strategy to enhance photocatalytic performance is to improve the transfer and separation efficiency of photogenerated carriers by building optimized heterojunctions. Herein, novel Bi4O5Br2/NH2-MIL-125(Ti)...
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Article
Open AccessShadow-aware image colorization
Significant advancements have been made in colorization in recent years, especially with the introduction of deep learning technology. However, challenges remain in accurately colorizing images under certain l...
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Article
Far-Infrared Therapy Based on Graphene Ameliorates High-Fat Diet-Induced Anxiety-Like Behavior in Obese Mice via Alleviating Intestinal Barrier Damage and Neuroinflammation
The consumption of a high-fat diet (HFD) has been implicated in the etiology of obesity and various neuropsychiatric disturbances, including anxiety and depression. Compelling evidence suggests that far-infrar...
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Article
Molecular docking-aided AIEgen design: concept, synthesis and applications
Aggregate-induced emission luminogens (AIEgens) have been widely used in biological imaging, chemical sensing, and disease treatments. The rational design and construction of AIEgens have received considerable...
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Article
Lethal pulmonary thromboembolism in mice induced by intravenous human umbilical cord mesenchymal stem cell-derived large extracellular vesicles in a dose- and tissue factor-dependent manner
Mesenchymal stem cell-derived extracellular vesicles (MSC-EVs) have obvious advantages over MSC therapy. But the strong procoagulant properties of MSC-EVs pose a potential risk of thromboembolism, an issue tha...
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Article
Open AccessNanoconfinement steers nonradical pathway transition in single atom fenton-like catalysis for improving oxidant utilization
The introduction of single-atom catalysts (SACs) into Fenton-like oxidation promises ultrafast water pollutant elimination, but the limited access to pollutants and oxidant by surface catalytic sites and the i...
