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  1. Article

    Open Access

    Hyperpolarized [1-13C] pyruvate MR spectroscopy detect altered glycolysis in the brain of a cognitively impaired mouse model fed high-fat diet

    Higher dietary intakes of saturated fatty acid increase the risk of develo** Alzheimer’s disease and dementia, and even in people without diabetes higher glucose levels may be a risk factor for dementia. The...

    Young-Suk Choi, Somang Kang, Sang-Yoon Ko, Saeram Lee, Jae Young Kim in Molecular Brain (2018)

  2. Article

    Open Access

    Hyperpolarized [1-13C]lactate flux increased in the hippocampal region in diabetic mice

    Increasing evidence suggests there is a relationship between cognitive impairment and metabolic dysfunction. Diabetes is a chronic disease, and metabolic factors affecting brain metabolisms, such as serum gluc...

    Young-Suk Choi, Jae Eun Song, Jong Eun Lee, Eosu Kim, Chul Hoon Kim in Molecular Brain (2019)