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Open AccessHyperpolarized [1-13C] pyruvate MR spectroscopy detect altered glycolysis in the brain of a cognitively impaired mouse model fed high-fat diet
Higher dietary intakes of saturated fatty acid increase the risk of develo** Alzheimer’s disease and dementia, and even in people without diabetes higher glucose levels may be a risk factor for dementia. The...
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Article
Open AccessHyperpolarized [1-13C]lactate flux increased in the hippocampal region in diabetic mice
Increasing evidence suggests there is a relationship between cognitive impairment and metabolic dysfunction. Diabetes is a chronic disease, and metabolic factors affecting brain metabolisms, such as serum gluc...