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Open AccessIntegrated proteomic and genomic analysis to identify predictive biomarkers for valproate response in bipolar disorder: a 6-month follow-up study
Several genetic studies have been undertaken to elucidate the intricate interplay between genetics and drug responses in bipolar disorder (BD). However, there has been notably limited research on biomarkers sp...
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Article
Open AccessInvestigation of gene–environment interactions in relation to tic severity
Tourette syndrome (TS) is a neuropsychiatric disorder with involvement of genetic and environmental factors. We investigated genetic loci previously implicated in Tourette syndrome and associated disorders in ...
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Article
Open AccessEffects of social defeat stress on dopamine D2 receptor isoforms and proteins involved in intracellular trafficking
Chronic social defeat stress induces depression and anxiety-like behaviors in rodents and also responsible for differentiating defeated animals into stress susceptible and resilient groups. The present study i...
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Article
Does Late Levodopa Administration Delay the Development of Dyskinesia in Patients with De Novo Parkinson’s Disease?
It remains controversial whether late levodopa administration is a reasonable approach to reducing the risk of levodopa-induced dyskinesia in Parkinson’s disease.
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Article
Open AccessReplicative genetic association study between functional polymorphisms in AVPR1A and social behavior scales of autism spectrum disorder in the Korean population
Arginine vasopressin has been shown to affect social and emotional behaviors, which is mediated by the arginine vasopressin receptor (AVPR1A). Genetic polymorphisms in the AVPR1A promoter region have been identif...
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Article
Asterixis in the leg induced by anterior cerebral artery infarction
Asterixis commonly occurs in a patient with metabolic encephalopathy, whereas focal brain lesions such as thalamus, cerebellum, or frontal area also cause focal or unilateral asterixis in the arms. We report a...
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Article
Source localization of intermittent rhythmic delta activity in a patient with acute confusional migraine: cross-spectral analysis using standardized low-resolution brain electromagnetic tomography (sLORETA)
Acute confusional migraine (ACM) shows typical electroencephalography (EEG) patterns of diffuse delta slowing and frontal intermittent rhythmic delta activity (FIRDA). The pathophysiology of ACM is still uncle...
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Article
Steroid responsive rhombencephalitis and optic neuritis with autoimmune thyroid disease
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Article
Possible anticipation associated with a novel splice site mutation in episodic ataxia type 2
Anticipation is a phenomenon characterized by decreasing age at onset and increasing severity of symptoms of a disease in successive generations within a pedigree. Anticipation mostly occurs in neurodegenerati...
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Article
Upbeat nystagmus due to a giant vertebral artery aneurysm
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Article
Musculoskeletal problems in Parkinson’s disease
Musculoskeletal problems are very common and are an important contributor to poor quality of life in Parkinson’s disease. However, they are under-appreciated, under-evaluated, and under-treated. This paper wil...
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Article
Neurologic signs in relation to cognitive function in subcortical ischemic vascular dementia: a CREDOS (Clinical Research Center for Dementia of South Korea) study
The objective of this study was to investigate the relationship between neurologic signs and cognitive dysfunction in subcortical ischemic vascular dementia (SIVD). 121 patients with SIVD were recruited from m...
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Article
Effects of statin and deferoxamine administration on neurological outcomes in a rat model of intracerebral hemorrhage
Deferoxamine (DFX), a potent iron-chelating agent, reduces brain edema and neuronal cell injury that develop due to the hemolysis cascade. Statins have neuroprotective effects via anti-inflammatory action and ...
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Article
Extranigral extension of structural midbrain lesions overshadows parkinsonism
We report on a clinicoanatomical analysis of five patients with structural midbrain lesions who shared severe nigrostriatal dopaminergic denervation but presented different involuntary movements. The main clin...
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Abstracts for the 6th Congress of Asian Sleep Research Society