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Article
Oculomics for sarcopenia prediction: a machine learning approach toward predictive, preventive, and personalized medicine
Sarcopenia is characterized by a gradual loss of skeletal muscle mass and strength with increased adverse outcomes. Recently, large-scale epidemiological studies have demonstrated a relationship between severa...
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Article
Extracellular nucleoprotein exacerbates influenza virus pathogenesis by activating Toll-like receptor 4 and the NLRP3 inflammasome
Host immune responses, such as those initiated by pattern recognition receptor (PRR) activation, are important for viral clearance and pathogenesis. However, little is known about the interactions of viral pro...
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Article
Autophagic response to exercise training in skeletal muscle with age
Autophagy, a highly conserved quality control mechanism, is essential for the maintenance of cellular homeostasis and for the orchestration of an efficient cellular response to stress. During aging, the effici...
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Article
Autophagic response to a single bout of moderate exercise in murine skeletal muscle
The effect of a single bout of exercise on autopahgy in murine gastrocnemius muscle was investigated. Autophagy is a process for the degradation system of cytoplasmic components, which may help maintain intrac...
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Article
Open AccessAntitumor immunity induced by tumor cells engineered to express a membrane-bound form of IL-2
Transduction of cytokine gene into tumor cells is a promising method of tumor therapy, but the value is limited by accompanying side effects. To focus antitumor immune response to tumor antigen-specific CTL, w...