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Combining E-ice-COLD-PCR and Pyrosequencing with Di-Base Addition (PDBA) Enables Sensitive Detection of Low-Abundance Mutations

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  1. Article

    Open Access

    Elevated Kir2.1/nuclear N2ICD defines a highly malignant subtype of non-WNT/SHH medulloblastomas

    Medulloblastoma (MB) is one of the most common childhood malignant brain tumors (WHO grade IV), traditionally divided into WNT, SHH, Group 3, and Group 4 subgroups based on the transcription profiles, somatic ...

    Yan-**a Wang, Haibo Wu, Yong Ren, Shengqing Lv in Signal Transduction and Targeted Therapy (2022)

  2. Article

    Open Access

    Autofluorescence of NADH is a new biomarker for sorting and characterizing cancer stem cells in human glioma

    The existing cell surface markers used for sorting glioma stem cells (GSCs) have obvious limitations, such as vulnerability to the enzymatic digestion and time-consuming labeling procedure. Reduced nicotinamid...

    Ye Yuan, Zexuan Yan, **gya Miao, Ruili Cai, Mengsi Zhang in Stem Cell Research & Therapy (2019)

  3. Article

    Open Access

    Capillary morphogenesis gene 2 maintains gastric cancer stem-like cell phenotype by activating a Wnt/β-catenin pathway

    A growing body of evidence shows that the development and progression of gastric cancer (GC) is mainly associated to the presence of gastric cancer stem-like cells (GCSLCs). However, it is unclear how GCSLC po...

    Chengdong Ji, Lang Yang, Wei**g Yi, Dongfang **ang, Yanxia Wang, Zhihua Zhou in Oncogene (2018)