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    Article

    Hepcidin1 Knockout Mice Display Defects in Bone Microarchitecture and Changes of Bone Formation Markers

    Iron accumulation is a risk factor of osteoporosis; mechanisms leading to iron-related bone loss are not fully determined. We sought to better understand the effect of chronic iron accumulation on bone over t...

    Guang Si Shen, Qing Yang, **g Long Jian, Guo Yang Zhao… in Calcified Tissue International (2014)

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    Article

    Therapeutic Effect of Deferoxamine on Iron Overload-Induced Inhibition of Osteogenesis in a Zebrafish Model

    Osteoporosis results from an imbalance in bone remodeling, in which osteoclastic bone resorption exceeds osteoblastic bone formation. Iron has recently been recognized as an independent risk factor for osteopo...

    Bin Chen, Yi-Lin Yan, Chen Liu, Lin Bo, Guang-Fei Li… in Calcified Tissue International (2014)