36 Result(s)

Article

Posttreatment liver function, but not baseline liver function stratifies patient survival after direct-acting antiviral treatment in decompensated cirrhosis with hepatitis C virus

The prognosis of cirrhosis is clearly stratified by liver function. Although direct-acting antiviral (DAA) has recently been used to eliminate hepatitis C virus (HCV), it is not clear whether liver function st...

Yuki Tahata, Hayato Hikita, Satoshi Mochida… in Journal of Gastroenterology (2023)

Article

A new model to estimate duration of survival in patients with hepatocellular carcinoma with BCLC intermediate stage

It is difficult to determine whether an individual therapy contributes to the elongation of survival because of the difficulty of organizing clinical research in patients who receive multiple treatments in HCC...

Masashi Ninomiya, Mio Tsuruoka, Jun Inoue, Atsushi Hiraoka… in Scientific Reports (2023)

Article

Prospects for treatment of esophageal varices considering the safety of endoscopic band ligation

Tomohiro Katsumi, Yoshiyuki Ueno in Hepatology International (2023)

Article

Modulation of AMPK/ TET2/ 5-hmC axis in response to metabolic alterations as a novel pathway for obesity-related colorectal cancer development

Obesity is a major risk factor for colorectal cancer (CRC). Sustained hyperglycemia destabilizes tumor suppressor ten-eleven translocation (TET) 2, which is a substrate of AMPK, thereby dysregulating 5-hydroxy...

Takashi Kon, Yu Sasaki, Yasuhiko Abe, Yusuke Onozato, Makoto Yagi… in Scientific Reports (2023)

Article

Association of the number of teeth and self-rated mastication with self-rated health in community-dwelling Japanese aged 40 years and older: the Yamagata cohort study

Self-rated health (SRH) is a predictive factor for health-related prognoses such as mortality. This study aimed to comprehensively investigate the risk factors for poor SRH in the general population of Japan, ...

Shigeo Ishikawa, Tsuneo Konta, Shinji Susa, Kenichi Ishizawa… in Scientific Reports (2022)

Article

Influence of skeletal muscle volume loss during lenvatinib treatment on prognosis in unresectable hepatocellular carcinoma: a multicenter study in Tohoku, Japan

Sarcopenia is associated with poor prognosis of patients with hepatocellular carcinoma (HCC). We investigated the association of skeletal muscle volume (SMV) and its change in HCC patients taking lenvatinib. I...

Masashi Fujita, Kazumichi Abe, Hidekatsu Kuroda, Takayoshi Oikawa… in Scientific Reports (2022)

Article

Novel genomic alteration in superficial esophageal squamous cell neoplasms in non-smoker non-drinker females

Alcohol consumption and smoking pose a significant risk for esophageal squamous cell neoplasia (ESCN) development in males; however, ESCN is often diagnosed in non-drinking and non-smoking females. The mechani...

Yusuke Onozato, Yu Sasaki, Yasuhiko Abe, Hidenori Sato, Makoto Yagi… in Scientific Reports (2021)

Article

Factors associated with health intentions and behaviour among health checkup participants in Japan

Health intentions and behaviours are essential for improving the health of individuals and society. This study used cross-sectional data from 20,155 health checkup participants in the Yamagata study to identif...

Takayuki Otsuka, Tsuneo Konta, Ri Sho, Tsukasa Osaki, Masayoshi Souri… in Scientific Reports (2021)

Article

Reliability of self-reported questionnaire for epidemiological investigation of Helicobacter pylori eradication in a population-based cohort study

General population-based cohort studies provide solid evidence on mass Helicobacter pylori (HP) eradication effects. Self-reported questionnaires are occasionally used in such studies to ascertain the HP eradicat...

Yu Sasaki, Yasuhiko Abe, Masakuni Shoji, Naoko Mizumoto… in Scientific Reports (2021)

Article

Association between milk and yogurt intake and mortality: a community-based cohort study (Yamagata study)

Dairy products are known as health-promoting foods. This study prospectively examined the association between milk and yogurt intake and mortality in a community-based population.

Akiko Nakanishi, Erika Homma, Tsukasa Osaki, Ri Sho, Masayoshi Souri… in BMC Nutrition (2021)

Article

Evidence-based clinical practice guidelines for Liver Cirrhosis 2020

The first edition of the clinical practice guidelines for liver cirrhosis was published in 2010, and the second edition was published in 2015 by the Japanese Society of Gastroenterology (JSGE). The revised thi...

Hitoshi Yoshiji, Sumiko Nagoshi, Takemi Akahane… in Journal of Gastroenterology (2021)

Article

The transition in the etiologies of hepatocellular carcinoma-complicated liver cirrhosis in a nationwide survey of Japan

We recently reported the real-world changes in the etiologies of liver cirrhosis (LC) based on nationwide survey data and assessed the etiologies of LC with hepatocellular carcinoma (HCC).

Hirayuki Enomoto, Yoshiyuki Ueno, Yoichi Hiasa… in Journal of Gastroenterology (2021)

Article

Utility of Claudin-3 in extracellular vesicles from human bile as biomarkers of cholangiocarcinoma

Extracellular vesicles (EVs) are released from all cells. Bile directly contacts bile duct tumor; bile-derived EVs may contain high concentrations of cancer biomarkers. We performed a proteomic analysis of hum...

Chisaki Ikeda, Hiroaki Haga, Naohiko Makino, Tatsutoshi Inuzuka… in Scientific Reports (2021)

Article

Somatic alterations and mutational burden are potential predictive factors for metachronous development of early gastric cancer

The risk of develo** metachronous gastric cancer (MGC) following curative endoscopic submucosal dissection (ESD) of early gastric cancer (EGC) remains even after eradicating Helicobacter pylori (HP) successfull...

Kazuhiro Sakuta, Yu Sasaki, Yasuhiko Abe, Hidenori Sato… in Scientific Reports (2020)

Article

Association between presence of 20 or more natural teeth and all-cause, cancer-related, and cardiovascular disease-related mortality: Yamagata (Takahata) prospective observational study

Several studies have surveyed the relationship between the presence of ≥ 20 natural teeth and mortality. However, very few have evaluated this association over a long-term follow-up of more than ten years with...

Shigeo Ishikawa, Tsuneo Konta, Shinji Susa, Kenichi Ishizawa… in BMC Oral Health (2020)

Article

Relationship between social support status and mortality in a community-based population: a prospective observational study (Yamagata study)

Social support, defined as the exchange of support in social relationships, plays a vital role in maintaining healthy behavior and mitigating the effects of stressors. This study investigated whether functiona...

Tsutomu Uzuki, Tsuneo Konta, Ritsuko Saito, Ri Sho, Tsukasa Osaki… in BMC Public Health (2020)

Article

Signet-ring cell carcinoma of the ampulla of Vater: a case diagnosed via repeated biopsies

Signet-ring cell carcinoma of the ampulla of Vater is a rare tumor. A 74-year-old woman presented with epigastric pain and was diagnosed with cholangitis. Her liver enzyme levels were elevated. Computed tomogr...

Chisaki Ikeda, Naohiko Makino, Akiko Matsuda… in Clinical Journal of Gastroenterology (2020)

Article

Association among chronic kidney disease, airflow limitation, and mortality in a community-based population: The Yamagata (Takahata) study

Chronic kidney disease (CKD) and chronic obstructive pulmonary disease (COPD) are known risk factors for mortality. In this study, we examined the overlap of CKD and airflow limitation (AFL) that characterises...

Natsuko Suzuki, Eri Matsuki, Akira Araumi, Sakiko Ashitomi… in Scientific Reports (2020)

Article

Transition in the etiology of liver cirrhosis in Japan: a nationwide survey

To assess the recent real-world changes in the etiologies of liver cirrhosis (LC) in Japan, we conducted a nationwide survey in the annual meeting of the Japan Society of Hepatology (JSH).

Hirayuki Enomoto, Yoshiyuki Ueno, Yoichi Hiasa… in Journal of Gastroenterology (2020)

Article

Steeper steps and pledge for inevitable responsibilities

Yoshiyuki Ueno, Hiroshi Seno in Journal of Gastroenterology (2020)