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Article
Open AccessCombined Rho-kinase inhibition and immunogenic cell death triggers and propagates immunity against cancer
Activation of T cell immune response is critical for the therapeutic efficacy of cancer immunotherapy. Current immunotherapies have shown remarkable clinical success against several cancers; however, significa...
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Protocol
Dynamic Light Scattering Analysis to Dissect Intermediates of SNARE-Mediated Membrane Fusion
Dynamic light scattering (DLS) spectroscopy provides rapid information on the size distribution of a large number of particles in a mixture. Vesicle sizes change during the merger of lipid bilayers, and DLS an...
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Article
Open AccessBoiling Histotripsy-induced Partial Mechanical Ablation Modulates Tumour Microenvironment by Promoting Immunogenic Cell Death of Cancers
Boiling histotripsy is a promising non-invasive High-Intensity Focused Ultrasound (HIFU) technique that employs HIFU mechanical effects to fractionate solid tumours without causing any significant thermal dama...
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Article
Open AccessPost-insertion technique to introduce targeting moieties in milk exosomes for targeted drug delivery
Recently, increased attention has been given on exosomes as ideal nanocarriers of drugs owing to their intrinsic properties that facilitate the transport of biomolecular cargos. However, large-scale exosome pr...