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  1. No Access

    Article

    Association of expression of GADD family genes and apoptosis in human kidney proximal tubular (HK-2) cells exposed to nephrotoxic drugs

    Nephrotoxicity is often referred to as a side effect of most drugs, but methods for effectively detecting nephrotoxicants still require development.

    Young-Eun Choi, Mi-Soon Kim, Yuna Ha, Yoon Cho… in Molecular & Cellular Toxicology (2022)

  2. No Access

    Article

    A study of cytotoxicity and genotoxicity of particulate matter (PM2.5) in human lung epithelial cells (A549)

    Exposure to airborne particulate matter (PM2.5), a PM with an aerodynamic diameter of less than 2.5 μm, is known to be associated with a variety of adverse health effects, particularly related to the respiratory ...

    Woong Kim, Seung-Chan Jeong, Chan-young Shin… in Molecular & Cellular Toxicology (2018)

  3. No Access

    Article

    Expression of exosomal and cellular microRNAs: as biomarkers for toluene, ethylbenzene, xylene (TEX) exposure

    Exosomes, small vesicles released by many cells, are associated with various biological processes and they can potentially be used for prognosis and therapy and as biomarkers of health. Thus, they are gaining ...

    Jung-hee Lim, Mi-Kyung Song, Yoon Cho, Woong Kim… in Molecular & Cellular Toxicology (2016)

  4. No Access

    Article

    Analysis of gene expression changes in relation to hepatotoxicity induced by perfluorinated chemicals in a human hepatoma cell line

    Perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA) represent a rising class of persistent organic pollutants termed perfluorinated chemicals (PFCs). In this study, hepatotoxic effects of PFCs w...

    Mi-Kyung Song, Yoon Cho, Seung-Chan Jeong… in Toxicology and Environmental Health Scienc… (2016)

  5. No Access

    Article

    Hexanal-induced changes in miRNA-mRNA interactions in A549 human alveolar epithelial cells

    Although hexanal is considered to be a major air pollutant the correlation between hexanal and health risk is largely unknown. Identifying aldehyde toxicity in eukaryotic cells will be useful for preventing an...

    Yoon Cho, Jung-hee Lim, Seung-Chan Jeong… in Toxicology and Environmental Health Scienc… (2015)

  6. No Access

    Article

    Gene expression profiling of human alveolar epithelial cells (A549 cells) exposed to atmospheric particulate matter 2.5 (PM2.5) collected from Seoul, Korea

    Many epidemiological and in vitro studies have shown that particulate matter 2.5 (PM2.5) is associated with adverse health effects in humans, especially respiratory morbidity and mortality1–3. While the mechanism...

    Seung-Chan Jeong, Chan-Young Shin, Mi-Kyung Song… in Molecular & Cellular Toxicology (2014)