-
Article
Open AccessAspirin inhibits rotavirus replication and alters rat gut microbial composition
Aspirin is widely used to treat various clinical symptoms. Evidence suggests that aspirin has antiviral properties, but little is known about its specific effect against rotavirus.
-
Article
Open AccessAnalysis of the intestinal microbial community altered during rotavirus infection in suckling mice
Rotavirus (RV) is a principal cause of diarrhea. However, there is a limited understanding regarding alteration of the gut microbial community structure and abundance during RV infection. This study was to cha...
-
Article
Characterization of a G9 group A rotavirus reassortant strain detected in **zhou, China, in 2018–2019
A novel rotavirus A (RVA) strain (JZ) was detected in RVA-positive stool specimens from three pediatric patients in **zhou, Liaoning Province, in 2018–2019. The electrophoresis pattern of the JZ strain showed...
-
Article
Open AccessThe effects of autophagy on the replication of Nelson Bay orthoreovirus
Nelson Bay orthoreovirus (NBV) was first isolated over 40 years ago from a fruit bat in Australia. Normally, NBV does not cause human diseases, but recently several NBV strains have been associated with human ...
-
Article
Open AccessPathogenicity and tissue distribution of grass carp reovirus after intraperitoneal administration
Grass carp reovirus (GCRV) is the causative agent of grass carp hemorrhage and causes significant loss of fingerlings. However, little is known about how the virus is distributed in organs and tissues. The aim...
-
Article
Open AccessPoly (I:C), an agonist of toll-like receptor-3, inhibits replication of the Chikungunya virus in BEAS-2B cells
Double-stranded RNA (dsRNA) and its mimic, polyinosinic acid: polycytidylic acid [Poly (I:C)], are recognized by toll-like receptor 3 (TLR3) and induce interferon (IFN)-β in many cell types. Poly (I:C) is the ...
-
Article
Elevated Th22 Cells Correlated with Th17 Cells in Patients with Rheumatoid Arthritis
T-helper (Th) 22 and Th17 cells are implicated in the pathogenesis of autoimmune diseases. The roles of Th22 cells in the pathophysiology of rheumatoid arthritis (RA) remain unsettled.
-
Article
Open AccessCharacterization of H5N1 influenza viruses isolated from humans in vitro
Since December 1997, highly pathogenic avian influenza A H5N1viruses have swept through poultry populations across Asian countries and been transmitted into African and European countries. We characterized 6 a...