315 Result(s)

Article

Correction: lncRNA THAP7-AS1, transcriptionally activated by SP1 and post-transcriptionally stabilized by METTL3-mediated m6A modification, exerts oncogenic properties by improving CUL4B entry into the nucleus

Hai-Ting Liu, Yong-**n Zou, Wen-jie Zhu, Sen-Liu… in Cell Death & Differentiation (2024)

Article

Evaluation of body shape as a human body composition assessment in isolated conditions and remote environments

Individuals in isolated and extreme environments can experience debilitating side-effects including significant decreases in fat-free mass (FFM) from disuse and inadequate nutrition. The objective of this stud...

Michael C. Wong, Jonathan P. Bennett, Lambert T. Leong, Yong E. Liu… in npj Microgravity (2024)

Article

Multi-omic analysis reveals the effects of interspecific hybridization on the synthesis of seed reserve polymers in a Triticum turgidum ssp. durum × Aegilops sharonensis amphidiploid

Wheat grain endosperm is mainly composed of proteins and starch. The contents and the overall composition of seed storage proteins (SSP) markedly affect the processing quality of wheat flour. Polyploidization ...

Qian Hu, **g Liu, **aolei Chen, Carlos Guzmán, Qiang Xu, Yazhou Zhang… in BMC Genomics (2024)

Article

AMPK targets PDZD8 to trigger carbon source shift from glucose to glutamine

The shift of carbon utilization from primarily glucose to other nutrients is a fundamental metabolic adaptation to cope with decreased blood glucose levels and the consequent decline in glucose oxidation. AMP-...

Mengqi Li, Yu Wang, **aoyan Wei, Wei-Feng Cai, Jianfeng Wu, Mingxia Zhu… in Cell Research (2024)

Article

The novel function of an orphan pheromone receptor reveals the sensory specializations of two potential distinct types of sex pheromones in noctuid moth

Sex pheromones play crucial role in mating behavior of moths, involving intricate recognition mechanisms. While insect chemical biology has extensively studied type I pheromones, type II pheromones remain larg...

Chenrui Wang, Song Cao, Chen Shi, Mengbo Guo… in Cellular and Molecular Life Sciences (2024)

Article

Electroacupuncture attenuates neuropathic pain via suppressing BIP-IRE-1α-mediated endoplasmic reticulum stress in the anterior cingulate cortex

Studies have suggested that endoplasmic reticulum stress (ERS) is involved in neurological dysfunction and that electroacupuncture (EA) attenuates neuropathic pain (NP) via undefined pathways. However, the rol...

Lin-Wei Ma, Yu-Fan Liu, Hui Zhang, Chang-Jun Huang, Ang Li… in Biological Research (2024)

Article

NAT10-mediated upregulation of GAS5 facilitates immune cell infiltration in non-small cell lung cancer via the MYBBP1A-p53/IRF1/type I interferon signaling axis

Interactions of tumor cells with immune cells in the tumor microenvironment play an important role during malignancy progression. We previously identified that GAS5 inhibited tumor development by suppressing prol...

Zimu Wang, **g Luo, Hairong Huang, Li Wang, Tangfeng Lv… in Cell Death Discovery (2024)

Article

Annotations of four high-quality indigenous chicken genomes identify more than one thousand missing genes in subtelomeric regions and micro-chromosomes with high G/C contents

Although multiple chicken genomes have been assembled and annotated, the numbers of protein-coding genes in chicken genomes and their variation among breeds are still uncertain due to the low quality of these ...

Siwen Wu, Tengfei Dou, Sisi Yuan, Shixiong Yan, Zhiqiang Xu, Yong Liu… in BMC Genomics (2024)

Article

Artificial selection footprints in indigenous and commercial chicken genomes

Although many studies have been done to reveal artificial selection signatures in commercial and indigenous chickens, a limited number of genes have been linked to specific traits. To identify more trait-relat...

Siwen Wu, Tengfei Dou, Kun Wang, Sisi Yuan, Shixiong Yan, Zhiqiang Xu… in BMC Genomics (2024)

Article

PICK1 inhibits the malignancy of nasopharyngeal carcinoma and serves as a novel prognostic marker

Although many important advances have been made in the treatment of nasopharyngeal carcinoma (NPC) in recent years, local recurrence and distant metastasis remain the main factors affecting NPC prognosis. Biom...

**aomin Ou, Yingzi Zhang, Yiqing Xu, Yi Liu, Wenzhi Tu, Chaosu Hu… in Cell Death & Disease (2024)

Article

FBXL8 inhibits post-myocardial infarction cardiac fibrosis by targeting Snail1 for ubiquitin-proteasome degradation

Abnormal cardiac fibrosis is the main pathological change of post-myocardial infarction (MI) heart failure. Although the E3 ubiquitin ligase FBXL8 is a key regulator in the cell cycle, cell proliferation, and ...

Ya Li, Caojian Zuo, **aoyu Wu, Yu Ding, Yong Wei, Songwen Chen… in Cell Death & Disease (2024)

Article

Mitochondria-associated endoplasmic reticulum membrane (MAM): a dark horse for diabetic cardiomyopathy treatment

Diabetic cardiomyopathy (DCM), an important complication of diabetes mellitus (DM), is one of the most serious chronic heart diseases and has become a major cause of heart failure worldwide. At present, the pa...

Yong Liu, **-Ling Huo, Kaidi Ren, Shaokang Pan, Hengdao Liu… in Cell Death Discovery (2024)

Article

Correlative single-cell hard X-ray computed tomography and X-ray fluorescence imaging

X-ray computed tomography (XCT) and X-ray fluorescence (XRF) imaging are two non-invasive imaging techniques to study cellular structures and chemical element distributions, respectively. However, correlative ...

Zihan Lin, **ao Zhang, Purbasha Nandi, Yuewei Lin, Liguo Wang… in Communications Biology (2024)

Article

HMGA1 drives chemoresistance in esophageal squamous cell carcinoma by suppressing ferroptosis

Chemotherapy is a primary treatment for esophageal squamous cell carcinoma (ESCC). Resistance to chemotherapeutic drugs is an important hurdle to effective treatment. Understanding the mechanisms underlying ch...

**g-Yu Yang, **n-Yuan Lei, Kai-Yue He, **-Rong Guo, Meng-Jie Liu… in Cell Death & Disease (2024)

Article

Bronchial epithelial transcriptomics and experimental validation reveal asthma severity-related neutrophilc signatures and potential treatments

Airway epithelial transcriptome analysis of asthma patients with different severity was used to disentangle the immune infiltration mechanisms affecting asthma exacerbation, which may be advantageous to asthma...

Qian Yan, **nxin Zhang, Yi **e, **g Yang, Chengxin Liu… in Communications Biology (2024)

Article

Population structure and adaptability analysis of Schizothorax o’connori based on whole-genome resequencing

Schizothorax o’connori is an endemic fish distributed in the upper and lower reaches of the Yarlung Zangbo River in China. It has experienced a fourth round of whole gene replication events and is a good model fo...

Kuo Gao, Zhi He, **xin **ong, Qiqi Chen, Bolin Lai, Fei Liu, ** Chen… in BMC Genomics (2024)

Article

Insights into the genetic variability and evolutionary dynamics of tomato spotted wilt orthotospovirus in China

Viral diseases are posing threat to annual production and quality of tobacco in China. Recently, tomato spotted wilt orthotospovirus (TSWV) has been reported to infect three major crops including tobacco. Curr...

Ali Kamran, Ying Li, Wanhong Zhang, Yubin Jiao, Tahir Farooq, Yong Wang… in BMC Genomics (2024)

Article

Fasting regulates mitochondrial function through lncRNA PRKCQ-AS1-mediated IGF2BPs in papillary thyroid carcinoma

Recurring evidence suggests that fasting has extensive antitumor effects in various cancers, including papillary thyroid carcinoma (PTC). However, the underlying mechanism of this relationship with PTC is unkn...

** Zhang, Yong Zhong, Lin Liu, Chengyou Jia, Haidong Cai… in Cell Death & Disease (2023)

Article

GBDT_KgluSite: An improved computational prediction model for lysine glutarylation sites based on feature fusion and GBDT classifier

Lysine glutarylation (Kglu) is one of the most important Post-translational modifications (PTMs), which plays significant roles in various cellular functions, including metabolism, mitochondrial processes, and...

**n Liu, Bao Zhu, **a-Wei Dai, Zhi-Ao Xu, Rui Li, Yuting Qian, Ya-** Lu… in BMC Genomics (2023)

Article

Correction: Alterations in exosomal miRNA profile upon epithelial-mesenchymal transition in human lung cancer cell lines

Yue-Ting Tang, Yi-Yao Huang, **g-Huan Li, Si-Hua Qin, Yong Xu, Tai-Xue An… in BMC Genomics (2023)