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Article
Open AccessOcular surface disorders associated with the use of dupilumab based on WHO VigiBase
Dupilumab is a dual inhibitor of interleukin-4 and interleukin-13 and is mainly used to treat moderate-to-severe atopic dermatitis. Post-marketing safety data related to dupilumab have been accumulated, and it...
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Article
Open AccessAuthor Correction: Structure-Activity Relationships of Baicalein and its Analogs as Novel TSLP Inhibitors
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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Article
Open AccessTumor microenvironment dictates regulatory T cell phenotype: Upregulated immune checkpoints reinforce suppressive function
Regulatory T (Treg) cells have an immunosuppressive function in cancer, but the underlying mechanism of immunosuppression in the tumor microenvironment (TME) is unclear.
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Article
Open AccessStructure-Activity Relationships of Baicalein and its Analogs as Novel TSLP Inhibitors
Thymic stromal lymphopoietin (TSLP) plays an important role in the differentiation and proliferation of Th2 cells, resulting in eosinophilic inflammation and numerous allergic diseases. Baicalein (1), a major com...
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Article
Open AccessIL-7 plays a critical role for the homeostasis of allergen-specific memory CD4 T cells in the lung and airways
Memory T cells respond rapidly to repeated antigen exposure and can maintain their population for extended periods through self-renewal. These characteristics of memory T cells have mainly been studied during ...
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Article
Anti-influenza effect of Cordyceps militaris through immunomodulation in a DBA/2 mouse model
The immune-modulatory as well as anti-influenza effects of Cordyceps extract were investigated using a DBA/2 mouse model. Three different concentrations of Cordyceps extract, red ginseng extract, or drinking wate...
