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  1. No Access

    Article

    Sulfated Glucuronorhamnoxylan from Capsosiphon fulvescens Ameliorates Osteoporotic Bone Resorption via Inhibition of Osteoclastic Cell Differentiation and Function In Vitro and In Vivo

    Excessive osteoclast differentiation and/or bone resorptive function causes a gradual loss of bone, leading to the pathogenesis of bone diseases such as osteoporosis (OP). In this study, a sulfated glucuronorh...

    Seong Cheol Kim, Hyeon Jeong Kim, Gi Eun Park, Chang Won Lee… in Marine Biotechnology (2022)

  2. No Access

    Article

    Regio-specific biotransformation of alizarin to alizarin methoxide with enhanced cytotoxicity against proliferative cells

    Alizarin has been reported to have an antigenotoxic activity along with an inhibitory effect on the tumor cell growth of human colon carcinoma cells. Alizarin was biotransformed into an O-methoxide derivative usi...

    Trang Thi Huyen Nguyen, Jang Mi Han… in Journal of Industrial Microbiology & Biote… (2020)

  3. No Access

    Article

    Low Molecular Weight Mannogalactofucans Derived from Undaria pinnatifida Induce Apoptotic Death of Human Prostate Cancer Cells In Vitro and In Vivo

    Low molecular weight mannogalactofucans (LMMGFs) prepared by enzymatic degradation of high molecular weight Undaria galactofucan (MF) were evaluated for their anti-cancer effects against human prostate cancer. Co...

    Jisun Lee, Seul Lee, Andriy Synytsya, Peter Capek, Chang Won Lee… in Marine Biotechnology (2018)

  4. No Access

    Article

    Metabolic engineering of Agrobacterium sp. ATCC31749 for curdlan production from cellobiose

    Curdlan is a commercial polysaccharide made by fermentation of Agrobacterium sp. Its anticipated expansion to larger volume markets demands improvement in its production efficiency. Metabolic engineering for stra...

    Hyun-Dong Shin, Long Liu, Mi-Kyoung Kim… in Journal of Industrial Microbiology & Biote… (2016)

  5. No Access

    Article

    Structural Features and Anti-coagulant Activity of the Sulphated Polysaccharide SPS-CF from a Green Alga Capsosiphon fulvescens

    Previously, we reported that the sulphated polysaccharides (SPS)-CF, a water-soluble polysaccharide isolated and purified from Korean green alga Maesaengi (Capsosiphon fulvescens, Chlorophyta), is a glucuronogala...

    Andriy Synytsya, Doo ** Choi, Radek Pohl, Ye Seul Na, Peter Capek… in Marine Biotechnology (2015)

  6. No Access

    Article

    Bioconversion of compactin into pravastatin by Streptomyces sp.

    Streptomyces sp. Y-110, isolated from soil, modified compactin to pravastatin, a therapeutic agent for hypercholesterolemia. In a batch culture, the highest production of pravastatin was 340 mg l−1 from 750 mg c...

    Joo-Woong Park, Joo-Kyung Lee, Tae-Jong Kwon, Dong-Hee Yi… in Biotechnology Letters (2003)

  7. No Access

    Article

    Extracellular production of a glycolipid biosurfactant, mannosylerythritol lipid, from Candida antarctica

    Candida antarctica (sp. SY16) required avegetable oil as the carbon source to produce a biosurfactant, mannosylerythritol lipid (MEL-SY16). Biosurfactant production was 31 g l−1 after 7 days in a batch culture a...

    Hee-Sik Kim, Jong-Woon Jeon, Hong-Won Lee, Yong-Il Park… in Biotechnology Letters (2002)

  8. No Access

    Article

    Expression of sfp gene and hydrocarbon degradation by Bacillus subtilis

    Bacillus subtilis C9 produces a lipopeptide-type biosurfactant, surfactin, and rapidly degrades alkanes up to a chain length of C19. The nucleotide sequence of the sfp gene cloned from B. subtilis C9 was determi...

    Hee-Sik Kim, Seong-Bin Kim, Seung-Hwan Park, Hee-Mock Oh… in Biotechnology Letters (2000)