57 Result(s)

Article

The Masquelet induced membrane technique with PRP-FG-nHA/PA66 scaffold can heal a rat large femoral bone defect

Masquelet membrane induction technology is one of the treatment strategies for large bone defect (LBD). However, the angiogenesis ability of induced membrane decreases with time and autologous bone grafting is...

**aoyu Wang, Yong Huang, Daqian Liu, Teng Zeng… in BMC Musculoskeletal Disorders (2024)

Article

Targeting TYK2 alleviates Rab27A-induced malignant progression of non-small cell lung cancer via disrupting IFNα-TYK2-STAT-HSPA5 axis

Rab27A is a small GTPase-mediating exosome secretion, which participates in tumorigenesis of multiple cancer types. Understanding the biological role of Rab27A in non-small cell lung cancer (NSCLC) is of great...

Yuanyuan Zeng, Jian Zhao, Zhengyan Wu, Yongkang Huang, Anqi Wang… in npj Precision Oncology (2024)

Article

Interleukin-6 on postoperative day three as an early predictor of infections following laparoscopic gastric cancer resection

To investigate the role of C-reactive protein (CRP), procalcitonin (PCT), and interleukin-6 (IL-6) as early predictors of infectious complications after laparoscopic gastric cancer surgery.

Yongzhou Huang, Lei Yang, Wenchang Yang, Pei Zhou, Qi Jiang, Weizhen Liu… in BMC Surgery (2024)

Article

Clinical features that predict the mortality risk in older patients with Omicron pneumonia: the MLWAP score

In December 2022, the Chinese suffered widespread Omicron of SARS-CoV-2 with variable symptom severity and outcome. We wanted to develop a scoring model to predict the mortality risk of older Omicron pneumonia...

Yongjian Pei, Ting Li, Chen Chen, Yongkang Huang… in Internal and Emergency Medicine (2024)

Article

Experimental study of a new technique for minimally invasive percutaneous nephrolithotomy: intelligent pressure-controlled minimally invasive percutaneous nephrolithotomy

To test the reliability and safety of a newly invented technique for minimally invasive percutaneous nephrolithotomy, intelligent pressure-controlled minimally invasive percutaneous nephrolithotomy (IPC-MPCNL).

Zhongsheng Yang, Leming Song, Yongming Huang, Hua Chen, Ting Sun in BMC Surgery (2024)

Article

Modulation of intestinal metabolites by calorie restriction and its association with gut microbiota in a xenograft model of colorectal cancer

Colorectal cancer (CRC) is a common malignant tumor, and its occurrence and development are closely related to dysbiosis of gut microbes. Previously, we found calorie restriction altered the composition of the...

Yuhuan Zhang, Lintao Dong, **ngchen Dai, Yongli Huang, Yu**g Gao… in Discover Oncology (2024)

Article

Discovering deaminases using AlphaFold2: a strategy to search for tool proteins for gene editing

Yongye Huang, Jianxin Jiang, Min Wu in Signal Transduction and Targeted Therapy (2024)

Article

Preoperative CT-based deep learning radiomics model to predict lymph node metastasis and patient prognosis in bladder cancer: a two-center study

To establish a model for predicting lymph node metastasis in bladder cancer (BCa) patients.

Rui Sun, Meng Zhang, Lei Yang, Shifeng Yang, Na Li, Yonghua Huang… in Insights into Imaging (2024)

Article

Efficacy of Qingpeng ointment (a Tibetan medicine) for acute gouty arthritis: a multi-center, randomized, double-blind, placebo-controlled trial

This study aims to assess the efficacy and safety of Qingpeng ointment (QPO), a Tibetan medicine for alleviating symptoms in individuals with acute gouty arthritis (AGA).

Ya-xi Shang, Shu-feng Wei, Ke-peng Yang… in BMC Complementary Medicine and Therapies (2024)

Article

Transmission chains of the first local outbreak cause by Delta VariantB.1.617.2 COVID-19 in Guangzhou, Southern China

The first local outbreak of Delta Variant B.1.617.2 COVID-19 of China occurred in Guangzhou city, south China, in May 2021. This study analyzed the transmission chains and local cluster characteristics of this...

Chun Chen, Ke Li, Yong Huang, Chaojun **e, Zongqiu Chen… in BMC Infectious Diseases (2024)

Article

RNA N6-methyladenosine-modified-binding protein YTHDF1 promotes prostate cancer progression by regulating androgen function-related gene TRIM68

There is no report about the direct relationship between m6A modification and androgen receptor (AR)-related genes in prostate cancer (PC). We aimed to study the mechanisms of m6A methylation in regulating the...

Qihong Nie, **aoyuan Wu, Yongming Huang, Tao Guo… in European Journal of Medical Research (2023)

Article

Association between chronic obstructive pulmonary disease and 28-day mortality in patients with sepsis: a retrospective study based on the MIMIC-III database

Sepsis is a common cause of mortality in critically ill patients, and chronic obstructive pulmonary disease (COPD) is one of the most common comorbidities in septic patients. However, the impact of COPD on pat...

Yubiao Chen, Lifei Lu, **cong Li, Baiyun Liu, Yu Zhang… in BMC Pulmonary Medicine (2023)

Article

Causal effects of inflammatory bowel diseases on the risk of kidney stone disease: a two-sample bidirectional mendelian randomization

Existing epidemiological observational studies have suggested interesting but inconsistent clinical correlations between inflammatory bowel disease (IBD), including Crohn’s disease (CD) and ulcerative colitis ...

Huayang Zhang, Yong Huang, Junyong Zhang, Huiyi Su, Chengguo Ge in BMC Urology (2023)

Article

Distribution and Characteristics of Ocular Biometric Parameters among a Chinese Population: A Hospital-Based Study

This study aimed to describe the distribution and characteristics of ocular biometric parameters among a large Chinese population.

**aohang Chen, Yongzhi Huang, Hao Chen, Longqian Liu in Ophthalmology and Therapy (2023)

Article

LZTFL1 inhibits kidney tumor cell growth by destabilizing AKT through ZNRF1-mediated ubiquitin proteosome pathway

LZTFL1 is a tumor suppressor located in chromosomal region 3p21.3 that is deleted frequently and early in various cancer types including the kidney cancer. However, its role in kidney tumorigenesis remains unk...

Jun Lu, Liang-min Fu, Yun Cao, Yong Fang, Jia-zheng Cao, Yi-hui Pan… in Oncogene (2023)

Article

Upregulation of β-catenin signaling represents a single common pathway leading to the various phenotypes of spinal degeneration and pain

Spine degeneration is an aging-related disease, but its molecular mechanisms remain unknown, although elevated β-catenin signaling has been reported to be involved in intervertebral disc degeneration. Here, we...

Ke Lu, Qingyun Wang, Hua Jiang, Jun Li, Zhou Yao, Yongcan Huang… in Bone Research (2023)

Article

Effects of age-related changes in trunk and lower limb range of motion on gait

The ability to walk is crucial for maintaining independence and a high quality of life among older adults. Although gait characteristics have been extensively studied in older adults, most studies have investi...

Meiling Zhai, Yongchao Huang, Shi Zhou, Yahong **… in BMC Musculoskeletal Disorders (2023)

Article

Oxymatrine ameliorates myocardial injury by inhibiting oxidative stress and apoptosis via the Nrf2/HO-1 and JAK/STAT pathways in type 2 diabetic rats

The necessity of increasing the efficiency of organ preservation has encouraged researchers to explore the mechanisms underlying diabetes-related myocardial injuries. This study intended to evaluate the protec...

Yongpan Huang, Bin He, Chong Song, **an Long… in BMC Complementary Medicine and Therapies (2023)

Article

Pneumonic-type invasive mucinous adenocarcinoma and infectious pneumonia: clinical and CT imaging analysis from multiple centers

Pneumonic-type invasive mucinous adenocarcinoma (IMA) was often misdiagnosed as pneumonia in clinic. However, the treatment of these two diseases is different.

Shuai Zhang, **nxin Yu, Yong Huang, Pei Nie, Yan Deng, Ning Mao… in BMC Pulmonary Medicine (2022)

Article

Monkeypox: epidemiology, pathogenesis, treatment and prevention

Monkeypox is a zoonotic disease that was once endemic in west and central Africa caused by monkeypox virus. However, cases recently have been confirmed in many nonendemic countries outside of Africa. WHO decla...

Yong Huang, Li Mu, Wei Wang in Signal Transduction and Targeted Therapy (2022)