-
Article
Open AccessTWEAK/Fn14 signalling driven super-enhancer reprogramming promotes pro-metastatic metabolic rewiring in triple-negative breast cancer
Triple Negative Breast Cancer (TNBC) is the most aggressive breast cancer subtype suffering from limited targeted treatment options. Following recent reports correlating Fibroblast growth factor-inducible 14 (...
-
Article
Multiscale engineering of molecular electrocatalysts for the rapid hydrogen evolution reaction
Molecular electrocatalysts have demonstrated potential for the hydrogen evolution reaction (HER) due to their well-defined structures and high intrinsic activities. Achieving rapid production of hydrogen requi...
-
Article
One-step electrospinning of cellulose acetate/chitosan/TiO2 fibrous membranes: efficient humic acid removal by synergistic adsorption and photocatalysis
The removal of contaminants in water purification is limited by the adsorption equilibrium, while the efficiency of photocatalytic oxidation is highly dependent on the adsorption process at the surface of phot...
-
Article
Eco-friendly fractionation of natural straws: sustainable ultralong room-temperature phosphorescence and super anti-ultraviolet materials
We demonstrate a new green solvent consisting of ionic liquid and polyol to achieve a selective fractionation of lignin from biomass. The lignin from corn straw is rich in syringyl unit and phenolic hydroxyl g...
-
Article
Open AccessDynamics of collagen oxidation and cross linking in regenerating and irreversibly infarcted myocardium
In mammalian hearts myocardial infarction produces a permanent collagen-rich scar. Conversely, in zebrafish a collagen-rich scar forms but is completely resorbed as the myocardium regenerates. The formation of...
-
Article
Open AccessUnveiling novel cell clusters and biomarkers in glioblastoma and its peritumoral microenvironment at the single-cell perspective
Glioblastoma (GBM) is a highly heterogeneous, recurrent and aggressively invasive primary malignant brain tumor. The heterogeneity of GBM results in poor targeted therapy. Therefore, the aim of this study is t...
-
Article
Open AccessPrevalence of ST1049-KL5 carbapenem-resistant Klebsiella pneumoniae with a blaKPC-2 and blaNDM-1 co-carrying hypertransmissible IncM1 plasmid
Infection caused by KPC and NDM carbapenemases co-producing Klebsiella pneumoniae (KPC_NDM_CRKP) poses serious public health concerns. Here, we elucidate the prevalence of a hypertransmissible lncM1 plasmid, pKPC...
-
Article
Study on the Association between anterior tooth Colour Preference based on the FAHP and individual factors
The relationship between tooth colour and individual satisfaction in oral aesthetics has long been a topic of interest. In this study, we utilized the fuzzy analytic hierarchy process (FAHP) to investigate the...
-
Article
Evaluation of the postharvest quality of Agaricus bisporus packed using PVA/SG-based active packaging film containing tea tree essential oil
In this study, an emerging type of packaging film containing polyvinyl alcohol and sesbania gum as the matrix and tea tree oil hydroxyapatite microspheres as the active ingredients was developed. The effect of...
-
Article
Multi-agent reinforcement learning for vehicular task offloading with multi-step trajectory prediction
With the development of multi-access edge computing (MEC), task offloading has become a promising paradigm to help the resource-constrained vehicles with their computation-intensive and time-sensitive tasks. R...
-
Article
Spatial Variation of Aquifer Permeability in the North China Plain from Large Magnitude Earthquake Signals
Permeability changes induced by earthquakes have been studied widely. However, basic questions still remain: what are the spatial differences in permeability changes induced by far-field earthquakes? Is there ...
-
Article
Evaluation of postharvest physiological parameters and shelf life of Agaricus bisporus by addition of anise essential oil Pickering emulsion to corn starch/cassia gum composite film
This corn starch (CS)/cassia gum (CG) composite film with the addition of aniseed essential oil (AEO) Pickering emulsion (PE) provides gas and moisture barrier, mechanical protection, as well as bacteriostatic...
-
Article
Review on role of electrical discharge drilling methods in fabricating micro holes: formation mechanism, defects characterization and mitigation strategies
Electrical discharge drilling (EDD), a non-contact manufacturing technology that brings the potential to fabricate microholes at low cost and relatively high efficiency, has aroused extensive attention at home...
-
Article
Review of Animal Models of Colorectal Cancer in Different Carcinogenesis Pathways
Colorectal cancer (CRC) is a common malignant tumor of the gastrointestinal tract with increasing morbidity and mortality. Exploring the factors affecting colorectal carcinogenesis and controlling its occurren...
-
Article
Open AccessManipulating Crystal Growth and Secondary Phase PbI2 to Enable Efficient and Stable Perovskite Solar Cells with Natural Additives
The novel ionic cellulose derivative with cyano-imidazolium cation and chloride anion, designed from natural cellulose, promotes the crystallization process, grain growth, and...
-
Article
Open AccessStudy on decision-making for orthodontic treatment plans based on analytic hierarchy process
Orthodontics is a common treatment for malocclusion and is essential for improving the oral health and aesthetics of patients. Currently, patients often rely on the clinical expertise and professional knowledg...
-
Article
Open AccessIntratumor injection of BCG Ag85A high-affinity peptides enhanced anti-tumor efficacy in PPD-positive melanoma
As one of the scheduled immunization vaccines worldwide, virtually all individuals have been vaccinated with BCG vaccine. In order to verify the hypothesis that delivering BCG high-affinity peptides to tumor a...
-
Article
Open AccessSTING agonist diABZI enhances the cytotoxicity of T cell towards cancer cells
Antigen-specific T cell receptor-engineered T cell (TCR-T) based immunotherapy has proven to be an effective method to combat cancer. In recent years, cross-talk between the innate and adaptive immune systems ...
-
Article
Analysis of heavy metal and polycyclic aromatic hydrocarbon pollution characteristics of a typical metal rolling industrial site based on data mining
With the transformation and upgrading of industries, the environmental problems caused by industrial residual contaminated sites are becoming increasingly prominent. Based on actual investigation cases, this s...
-
Article
Transcriptome analysis of primary culture cells of Chinese soft-shelled turtle transfected with polyinosinic-polycytidylic acid (poly I:C) and treated with aqueous extract of Whitmania pigra
The present study aimed to investigate the transcriptomic response to virus simulant (polyinosinic-polycytidylic acid, poly I:C), and to determine if the aqueous leech (Whitmania pigra) extract has the function o...
