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Article
Open AccessA study of impact of climate change on the U.S. stock market as exemplified by the NASDAQ 100 index constituents
This paper employs an innovative event study methodology to demonstrate the impact of climate change on the NASDAQ index from the unique perspective of extreme weather events. This is achieved through the appl...
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Article
Open AccessCorrelations of pathomorphological parameters between lesions at the invasive front and lymph node metastases in colorectal cancer: a retrospective clinical study
Lymph node (LN) metastasis is one of the most important indicators to evaluate stage, choose treatment strategy, and predict outcome of colorectal cancer (CRC). The morphological correlation between primary tu...
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Article
JoCaD: a joint training method by combining consistency and diversity
Noisy labels due to mistakes in manual labeling or data collecting are challenging for the expansion of deep neural network applications. Current robust network learning methods such as Decoupling, Co-teaching...
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Article
Open AccessProgrammed Cell Death-Related Gene Signature Associated with Prognosis and Immune Infiltration and the Roles of HMOX1 in the Proliferation and Apoptosis were Investigated in Uveal Melanoma
Uveal melanoma (UVM) is the most common primary ocular malignancy, with a wide range of symptoms and outcomes. The programmed cell death (PCD) plays an important role in tumor development, diagnosis, and progn...
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Article
Low legume-grass seeding ratio combined with phosphorus fertilization promotes forage yield and soil quality in managed grasslands
Legume-grass mixtures are often used to increase forage yield and soil fertility in managed grasslands, but it remains unclear whether these benefits could be further improved by utilizing optimal legume-grass...
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Article
An improved polygon mesh generation and its application in SBFEM using NURBS boundary
Aiming to address the challenge of inaccurately describing the curve boundary of the complex design domain in traditional finite element mesh, this paper proposes an improved polygon mesh generation and polygo...
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Article
An Improved Thermal Conductivity Measurement Scheme for Macroscopic Graphitic Films Using the Laser Flash Method
Achieving efficient thermal management urges to exploit high-thermal-conductivity materials to satisfy the boosted demand of heat dissipation. It is critical to adopt standardized characterization protocols to...
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Article
Open AccessLanthanide-regulating Ru-O covalency optimizes acidic oxygen evolution electrocatalysis
Precisely modulating the Ru-O covalency in RuOx for enhanced stability in proton exchange membrane water electrolysis is highly desired. However, transition metals with d-valence electrons, which were doped into ...
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Article
CD56bright NK cell expansion correlated with EBV reactivation control post allogeneic hematopoietic stem cell transplantation
Natural killer (NK) cells are equipped with anti-Epstein-Barr virus (EBV) function, however, whether EBV infection will affect NK cells reconstitution after allogeneic hematopoietic stem cell transplantation (...
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Article
Open AccessA cell atlas of the adult female Aedes aegypti midgut revealed by single-cell RNA sequencing
Aedes aegypti is a primary vector for transmitting various arboviruses, including Yellow fever, dengue and Zika virus. The mosquito midgut is the principal organ for blood meal digestion, nutrient absorption and ...
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Article
Open AccessIntegrated analysis of the role of PR/SET domain 14 in gastric cancer
Gastric cancer is one of the most common tumors worldwide, and most patients are deprived of treatment options when diagnosed at advanced stages. PRDM14 has carcinogenic potential in breast and non-small cell ...
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Article
Polyvinyl alcohol-enhanced intelligent films for the accurate monitoring of pH via anthocyanin-induced color changes
In this paper, an intelligent film was developed using the cast film process, with acetylated distarch phosphate (ADSP) and polyvinyl alcohol (PVA) as substrates. Red cabbage anthocyanin extracts (RCAE) were i...
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Article
Open AccessNG2 glia protect against prion neurotoxicity by inhibiting microglia-to-neuron prostaglandin E2 signaling
Oligodendrocyte-lineage cells, including NG2 glia, undergo prominent changes in various neurodegenerative disorders. Here, we identify a neuroprotective role for NG2 glia against prion toxicity. NG2 glia were ...
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Article
Open AccessPacidusin B isolated from Phyllanthus acidus triggers ferroptotic cell death in HT1080 cells
Cancer cells generally exhibit ‘iron addiction’ phenotypes, which contribute to their vulnerability to ferroptosis inducers. Ferroptosis is a newly discovered form of programmed cell death caused by iron-depen...
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Article
Metal bond strength regulation enables large-scale synthesis of intermetallic nanocrystals for practical fuel cells
Structurally ordered L10-PtM (M = Fe, Co, Ni and so on) intermetallic nanocrystals, benefiting from the chemically ordered structure and higher stability, are one of the best electrocatalysts used for fuel cells....
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Article
Open AccessEstimating effects of whole grain consumption on type 2 diabetes, colorectal cancer and cardiovascular disease: a burden of proof study
Previous studies on whole grain consumption had inconsistent findings and lacked quantitative assessments of evidence quality. Therefore, we aimed to summarize updated findings using the Burden of Proof analys...
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Article
Open AccessA novel easy-to-desorb eluant contributes to address environmental contamination of African swine fever virus
African swine fever virus (ASFV) is a highly pathogenic and rapidly disseminated virus with strong viability in the environment, suggesting the importance of environmental detection for prevention and control ...
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Article
Open AccessAdvances and perspectives in environmental health research in China
Environmental health research aims to identify environmental conditions suitable for the healthy living and reproduction of human beings. Through the interdisciplinary research bridging environmental sciences ...
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Article
Open AccessA protoplast-based transient gene expression assay for the identification of heat and oxidative stress-regulatory genes in perennial ryegrass
With the accumulating omics data, an efficient and time-saving transient assay to express target genes is desired. Mesophyll protoplasts, maintaining most stress-physiological responses and cellular activities...
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Article
Open AccessHuman pan-cancer analysis of the predictive biomarker for the CDKN3
Cell cycle protein-dependent kinase inhibitor protein 3 (CDKN3), as a member of the protein kinase family, has been demonstrated to exhibit oncogenic properties in several tumors. However, there are no pan-car...
