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Article

Anxiolytic effect of antidiabetic metformin is mediated by AMPK activation in mPFC inhibitory neurons

Diabetic patients receiving the antidiabetic drug metformin have been observed to exhibit a lower prevalence of anxiety disorders, yet the precise mechanism behind this phenomenon is unclear. In our study, we ...

Yong-mei Zhang, Hai-chao Zong, Ying-bei Qi, Liu-liu Chang… in Molecular Psychiatry (2023)